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Macrophage-Derived 25-Hydroxycholesterol Promotes Vascular Inflammation, Atherogenesis, and Lesion Remodeling.
Canfrán-Duque A, Rotllan N, Zhang X, Andrés-Blasco I, Thompson BM, Sun J, Price NL, Fernández-Fuertes M, Fowler JW, Gómez-Coronado D, Sessa WC, Giannarelli C, Schneider RJ, Tellides G, McDonald JG, Fernández-Hernando C, Suárez Y. Canfrán-Duque A, et al. Among authors: mcdonald jg. Circulation. 2023 Jan 31;147(5):388-408. doi: 10.1161/CIRCULATIONAHA.122.059062. Epub 2022 Nov 23. Circulation. 2023. PMID: 36416142 Free PMC article.
A mouse macrophage lipidome.
Dennis EA, Deems RA, Harkewicz R, Quehenberger O, Brown HA, Milne SB, Myers DS, Glass CK, Hardiman G, Reichart D, Merrill AH Jr, Sullards MC, Wang E, Murphy RC, Raetz CR, Garrett TA, Guan Z, Ryan AC, Russell DW, McDonald JG, Thompson BM, Shaw WA, Sud M, Zhao Y, Gupta S, Maurya MR, Fahy E, Subramaniam S. Dennis EA, et al. Among authors: mcdonald jg. J Biol Chem. 2010 Dec 17;285(51):39976-85. doi: 10.1074/jbc.M110.182915. Epub 2010 Oct 5. J Biol Chem. 2010. PMID: 20923771 Free PMC article.
27-Hydroxycholesterol promotes cell-autonomous, ER-positive breast cancer growth.
Wu Q, Ishikawa T, Sirianni R, Tang H, McDonald JG, Yuhanna IS, Thompson B, Girard L, Mineo C, Brekken RA, Umetani M, Euhus DM, Xie Y, Shaul PW. Wu Q, et al. Among authors: mcdonald jg. Cell Rep. 2013 Nov 14;5(3):637-45. doi: 10.1016/j.celrep.2013.10.006. Epub 2013 Nov 7. Cell Rep. 2013. PMID: 24210818 Free PMC article.
Bazedoxifene and conjugated estrogen prevent diet-induced obesity, hepatic steatosis, and type 2 diabetes in mice without impacting the reproductive tract.
Barrera J, Chambliss KL, Ahmed M, Tanigaki K, Thompson B, McDonald JG, Mineo C, Shaul PW. Barrera J, et al. Among authors: mcdonald jg. Am J Physiol Endocrinol Metab. 2014 Aug 1;307(3):E345-54. doi: 10.1152/ajpendo.00653.2013. Epub 2014 Jun 17. Am J Physiol Endocrinol Metab. 2014. PMID: 24939737 Free article.
Cell-specific discrimination of desmosterol and desmosterol mimetics confers selective regulation of LXR and SREBP in macrophages.
Muse ED, Yu S, Edillor CR, Tao J, Spann NJ, Troutman TD, Seidman JS, Henke A, Roland JT, Ozeki KA, Thompson BM, McDonald JG, Bahadorani J, Tsimikas S, Grossman TR, Tremblay MS, Glass CK. Muse ED, et al. Among authors: mcdonald jg. Proc Natl Acad Sci U S A. 2018 May 15;115(20):E4680-E4689. doi: 10.1073/pnas.1714518115. Epub 2018 Apr 9. Proc Natl Acad Sci U S A. 2018. PMID: 29632203 Free PMC article.
134 results