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Donor heart ischemic time can be extended beyond 9 hours using hypothermic machine perfusion in sheep.
See Hoe LE, Li Bassi G, Wildi K, Passmore MR, Bouquet M, Sato K, Heinsar S, Ainola C, Bartnikowski N, Wilson ES, Hyslop K, Skeggs K, Obonyo NG, Shuker T, Bradbury L, Palmieri C, Engkilde-Pedersen S, McDonald C, Colombo SM, Wells MA, Reid JD, O'Neill H, Livingstone S, Abbate G, Haymet A, Jung JS, Sato N, James L, He T, White N, Redd MA, Millar JE, Malfertheiner MV, Molenaar P, Platts D, Chan J, Suen JY, McGiffin DC, Fraser JF. See Hoe LE, et al. Among authors: mcdonald c. J Heart Lung Transplant. 2023 Aug;42(8):1015-1029. doi: 10.1016/j.healun.2023.03.020. Epub 2023 Apr 7. J Heart Lung Transplant. 2023. PMID: 37031869 Free article.
A clinically relevant sheep model of orthotopic heart transplantation 24 h after donor brainstem death.
See Hoe LE, Wildi K, Obonyo NG, Bartnikowski N, McDonald C, Sato K, Heinsar S, Engkilde-Pedersen S, Diab S, Passmore MR, Wells MA, Boon AC, Esguerra A, Platts DG, James L, Bouquet M, Hyslop K, Shuker T, Ainola C, Colombo SM, Wilson ES, Millar JE, Malfertheiner MV, Reid JD, O'Neill H, Livingstone S, Abbate G, Sato N, He T, von Bahr V, Rozencwajg S, Byrne L, Pimenta LP, Marshall L, Nair L, Tung JP, Chan J, Haqqani H, Molenaar P, Li Bassi G, Suen JY, McGiffin DC, Fraser JF. See Hoe LE, et al. Among authors: mcdonald c. Intensive Care Med Exp. 2021 Dec 24;9(1):60. doi: 10.1186/s40635-021-00425-4. Intensive Care Med Exp. 2021. PMID: 34950993 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 35567473
Compromised right ventricular contractility in an ovine model of heart transplantation following 24 h donor brain stem death.
Wells MA, See Hoe LE, Molenaar P, Pedersen S, Obonyo NG, McDonald CI, Mo W, Bouquet M, Hyslop K, Passmore MR, Bartnikowski N, Suen JY, Peart JN, McGiffin DC, Fraser JF; Dead Heart Project. Wells MA, et al. Among authors: mcdonald ci. Pharmacol Res. 2021 Jul;169:105631. doi: 10.1016/j.phrs.2021.105631. Epub 2021 Apr 24. Pharmacol Res. 2021. PMID: 33905863
Oxidative stress during extracorporeal circulation.
McDonald CI, Fraser JF, Coombes JS, Fung YL. McDonald CI, et al. Eur J Cardiothorac Surg. 2014 Dec;46(6):937-43. doi: 10.1093/ejcts/ezt637. Epub 2014 Jan 30. Eur J Cardiothorac Surg. 2014. PMID: 24482384 Review.
2,963 results