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Genomics-guided pre-clinical development of cancer therapies.
Francies HE, McDermott U, Garnett MJ. Francies HE, et al. Among authors: mcdermott u. Nat Cancer. 2020 May;1(5):482-492. doi: 10.1038/s43018-020-0067-x. Epub 2020 May 22. Nat Cancer. 2020. PMID: 35121986 Review.
Genomics and the continuum of cancer care.
McDermott U, Downing JR, Stratton MR. McDermott U, et al. N Engl J Med. 2011 Jan 27;364(4):340-50. doi: 10.1056/NEJMra0907178. N Engl J Med. 2011. PMID: 21268726 Free article. Review. No abstract available.
Systematic identification of genomic markers of drug sensitivity in cancer cells.
Garnett MJ, Edelman EJ, Heidorn SJ, Greenman CD, Dastur A, Lau KW, Greninger P, Thompson IR, Luo X, Soares J, Liu Q, Iorio F, Surdez D, Chen L, Milano RJ, Bignell GR, Tam AT, Davies H, Stevenson JA, Barthorpe S, Lutz SR, Kogera F, Lawrence K, McLaren-Douglas A, Mitropoulos X, Mironenko T, Thi H, Richardson L, Zhou W, Jewitt F, Zhang T, O'Brien P, Boisvert JL, Price S, Hur W, Yang W, Deng X, Butler A, Choi HG, Chang JW, Baselga J, Stamenkovic I, Engelman JA, Sharma SV, Delattre O, Saez-Rodriguez J, Gray NS, Settleman J, Futreal PA, Haber DA, Stratton MR, Ramaswamy S, McDermott U, Benes CH. Garnett MJ, et al. Among authors: mcdermott u. Nature. 2012 Mar 28;483(7391):570-5. doi: 10.1038/nature11005. Nature. 2012. PMID: 22460902 Free PMC article.
MED12 controls the response to multiple cancer drugs through regulation of TGF-β receptor signaling.
Huang S, Hölzel M, Knijnenburg T, Schlicker A, Roepman P, McDermott U, Garnett M, Grernrum W, Sun C, Prahallad A, Groenendijk FH, Mittempergher L, Nijkamp W, Neefjes J, Salazar R, Ten Dijke P, Uramoto H, Tanaka F, Beijersbergen RL, Wessels LF, Bernards R. Huang S, et al. Among authors: mcdermott u. Cell. 2012 Nov 21;151(5):937-50. doi: 10.1016/j.cell.2012.10.035. Cell. 2012. PMID: 23178117 Free PMC article.
Genomics of Drug Sensitivity in Cancer (GDSC): a resource for therapeutic biomarker discovery in cancer cells.
Yang W, Soares J, Greninger P, Edelman EJ, Lightfoot H, Forbes S, Bindal N, Beare D, Smith JA, Thompson IR, Ramaswamy S, Futreal PA, Haber DA, Stratton MR, Benes C, McDermott U, Garnett MJ. Yang W, et al. Among authors: mcdermott u. Nucleic Acids Res. 2013 Jan;41(Database issue):D955-61. doi: 10.1093/nar/gks1111. Epub 2012 Nov 23. Nucleic Acids Res. 2013. PMID: 23180760 Free PMC article.
VS-5584, a novel and highly selective PI3K/mTOR kinase inhibitor for the treatment of cancer.
Hart S, Novotny-Diermayr V, Goh KC, Williams M, Tan YC, Ong LC, Cheong A, Ng BK, Amalini C, Madan B, Nagaraj H, Jayaraman R, Pasha KM, Ethirajulu K, Chng WJ, Mustafa N, Goh BC, Benes C, McDermott U, Garnett M, Dymock B, Wood JM. Hart S, et al. Among authors: mcdermott u. Mol Cancer Ther. 2013 Feb;12(2):151-61. doi: 10.1158/1535-7163.MCT-12-0466. Epub 2012 Dec 27. Mol Cancer Ther. 2013. PMID: 23270925 Free PMC article.
Editorial overview: cancer genomics: kill it. Kill it dead.
Adams D, McDermott U. Adams D, et al. Among authors: mcdermott u. Curr Opin Genet Dev. 2014 Feb;24:v-vi. doi: 10.1016/j.gde.2013.12.006. Epub 2014 Feb 23. Curr Opin Genet Dev. 2014. PMID: 24569083 No abstract available.
179 results