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Fecal microbiota transplant overcomes resistance to anti-PD-1 therapy in melanoma patients.
Davar D, Dzutsev AK, McCulloch JA, Rodrigues RR, Chauvin JM, Morrison RM, Deblasio RN, Menna C, Ding Q, Pagliano O, Zidi B, Zhang S, Badger JH, Vetizou M, Cole AM, Fernandes MR, Prescott S, Costa RGF, Balaji AK, Morgun A, Vujkovic-Cvijin I, Wang H, Borhani AA, Schwartz MB, Dubner HM, Ernst SJ, Rose A, Najjar YG, Belkaid Y, Kirkwood JM, Trinchieri G, Zarour HM. Davar D, et al. Among authors: mcculloch ja. Science. 2021 Feb 5;371(6529):595-602. doi: 10.1126/science.abf3363. Science. 2021. PMID: 33542131 Free PMC article. Clinical Trial.
Wild Mouse Gut Microbiota Promotes Host Fitness and Improves Disease Resistance.
Rosshart SP, Vassallo BG, Angeletti D, Hutchinson DS, Morgan AP, Takeda K, Hickman HD, McCulloch JA, Badger JH, Ajami NJ, Trinchieri G, Pardo-Manuel de Villena F, Yewdell JW, Rehermann B. Rosshart SP, et al. Among authors: mcculloch ja. Cell. 2017 Nov 16;171(5):1015-1028.e13. doi: 10.1016/j.cell.2017.09.016. Epub 2017 Oct 19. Cell. 2017. PMID: 29056339 Free PMC article.
Gut microbiome-mediated bile acid metabolism regulates liver cancer via NKT cells.
Ma C, Han M, Heinrich B, Fu Q, Zhang Q, Sandhu M, Agdashian D, Terabe M, Berzofsky JA, Fako V, Ritz T, Longerich T, Theriot CM, McCulloch JA, Roy S, Yuan W, Thovarai V, Sen SK, Ruchirawat M, Korangy F, Wang XW, Trinchieri G, Greten TF. Ma C, et al. Among authors: mcculloch ja. Science. 2018 May 25;360(6391):eaan5931. doi: 10.1126/science.aan5931. Science. 2018. PMID: 29798856 Free PMC article.
An Interleukin-23-Interleukin-22 Axis Regulates Intestinal Microbial Homeostasis to Protect from Diet-Induced Atherosclerosis.
Fatkhullina AR, Peshkova IO, Dzutsev A, Aghayev T, McCulloch JA, Thovarai V, Badger JH, Vats R, Sundd P, Tang HY, Kossenkov AV, Hazen SL, Trinchieri G, Grivennikov SI, Koltsova EK. Fatkhullina AR, et al. Among authors: mcculloch ja. Immunity. 2018 Nov 20;49(5):943-957.e9. doi: 10.1016/j.immuni.2018.09.011. Epub 2018 Oct 30. Immunity. 2018. PMID: 30389414 Free PMC article.
Laboratory mice born to wild mice have natural microbiota and model human immune responses.
Rosshart SP, Herz J, Vassallo BG, Hunter A, Wall MK, Badger JH, McCulloch JA, Anastasakis DG, Sarshad AA, Leonardi I, Collins N, Blatter JA, Han SJ, Tamoutounour S, Potapova S, Foster St Claire MB, Yuan W, Sen SK, Dreier MS, Hild B, Hafner M, Wang D, Iliev ID, Belkaid Y, Trinchieri G, Rehermann B. Rosshart SP, et al. Among authors: mcculloch ja. Science. 2019 Aug 2;365(6452):eaaw4361. doi: 10.1126/science.aaw4361. Epub 2019 Aug 1. Science. 2019. PMID: 31371577 Free PMC article.
Microbiome as an Immunological Modifier.
Kumar M, Singh P, Murugesan S, Vetizou M, McCulloch J, Badger JH, Trinchieri G, Al Khodor S. Kumar M, et al. Methods Mol Biol. 2020;2055:595-638. doi: 10.1007/978-1-4939-9773-2_27. Methods Mol Biol. 2020. PMID: 31502171 Free PMC article.
Infection trains the host for microbiota-enhanced resistance to pathogens.
Stacy A, Andrade-Oliveira V, McCulloch JA, Hild B, Oh JH, Perez-Chaparro PJ, Sim CK, Lim AI, Link VM, Enamorado M, Trinchieri G, Segre JA, Rehermann B, Belkaid Y. Stacy A, et al. Among authors: mcculloch ja. Cell. 2021 Feb 4;184(3):615-627.e17. doi: 10.1016/j.cell.2020.12.011. Epub 2021 Jan 15. Cell. 2021. PMID: 33453153 Free PMC article.
86 results