McCoy MA - Search Results

1

NMR Data-Driven Docking of HDM2-Inhibitor Complexes.

Fradera X, Reutershan MH, Machacek MR, Trotter BW, McCoy MA. Fradera X, et al. Among authors: mccoy ma. Chembiochem. 2022 Mar 18;23(6):e202100570. doi: 10.1002/cbic.202100570. Epub 2022 Feb 21. Chembiochem. 2022. PMID: 35104390

2

Discovery of MK-4688: an Efficient Inhibitor of the HDM2-p53 Protein-Protein Interaction.

Reutershan MH, Machacek MR, Altman MD, Bogen S, Cai M, Cammarano C, Chen D, Christopher M, Cryan J, Daublain P, Fradera X, Geda P, Goldenblatt P, Hill AD, Kemper RA, Kutilek V, Li C, Martinez M, McCoy M, Nair L, Pan W, Thompson CF, Scapin G, Shizuka M, Spatz ML, Steinhuebel D, Sun B, Voss ME, Wang X, Yang L, Yeh TC, Dussault I, Marshall CG, Trotter BW. Reutershan MH, et al. J Med Chem. 2021 Nov 11;64(21):16213-16241. doi: 10.1021/acs.jmedchem.1c01524. Epub 2021 Oct 29. J Med Chem. 2021. PMID: 34714078

3

NMR Assessment of Therapeutic Peptides and Proteins: Correlations That Reveal Interactions and Motions.

Falk BT, Liang Y, Bailly M, Raoufi F, Kekec A, Pissarnitski D, Feng D, Yan L, Lin S, Fayadat-Dilman L, McCoy MA. Falk BT, et al. Among authors: mccoy ma. Chembiochem. 2020 Feb 3;21(3):315-319. doi: 10.1002/cbic.201900296. Epub 2019 Oct 24. Chembiochem. 2020. PMID: 31283075

4

Diffusion Profiling of Therapeutic Proteins by Using Solution NMR Spectroscopy.

Falk BT, Liang Y, McCoy MA. Falk BT, et al. Among authors: mccoy ma. Chembiochem. 2019 Apr 1;20(7):896-899. doi: 10.1002/cbic.201800631. Epub 2019 Mar 4. Chembiochem. 2019. PMID: 30515922

5

Quantification of natural abundance NMR data differentiates the solution behavior of monoclonal antibodies and their fragments.

Ban D, Rice CT, McCoy MA. Ban D, et al. Among authors: mccoy ma. MAbs. 2021 Jan-Dec;13(1):1978132. doi: 10.1080/19420862.2021.1978132. MAbs. 2021. PMID: 34612804 Free PMC article.

6

Structures of protein-protein complexes are docked using only NMR restraints from residual dipolar coupling and chemical shift perturbations.

McCoy MA, Wyss DF. McCoy MA, et al. J Am Chem Soc. 2002 Mar 13;124(10):2104-5. doi: 10.1021/ja017242z. J Am Chem Soc. 2002. PMID: 11878950

7

Spatial localization of ligand binding sites from electron current density surfaces calculated from NMR chemical shift perturbations.

McCoy MA, Wyss DF. McCoy MA, et al. J Am Chem Soc. 2002 Oct 2;124(39):11758-63. doi: 10.1021/ja026166c. J Am Chem Soc. 2002. PMID: 12296743

8

Profiling Insulin Oligomeric States by ¹H NMR Spectroscopy for Formulation Development of Ultra-Rapid-Acting Insulin.

Falk BT, Liang Y, McCoy MA. Falk BT, et al. Among authors: mccoy ma. J Pharm Sci. 2020 Jan;109(1):922-926. doi: 10.1016/j.xphs.2019.07.025. Epub 2019 Aug 23. J Pharm Sci. 2020. PMID: 31449814

9

Investigating protein-excipient interactions of a multivalent V_HH therapeutic protein using NMR spectroscopy.

Panchal J, Falk BT, Antochshuk V, McCoy MA. Panchal J, et al. Among authors: mccoy ma. MAbs. 2022 Jan-Dec;14(1):2124902. doi: 10.1080/19420862.2022.2124902. MAbs. 2022. PMID: 36166705 Free PMC article.

10

NMR Binding and Functional Assays for Detecting Inhibitors of S. aureus MnaA.

Hou Y, Mayhood T, Sheth P, Tan CM, Labroli M, Su J, Wyss DF, Roemer T, McCoy MA. Hou Y, et al. Among authors: mccoy ma. J Biomol Screen. 2016 Jul;21(6):579-89. doi: 10.1177/1087057116640199. Epub 2016 Mar 29. J Biomol Screen. 2016. PMID: 27028606

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