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Activation of the Mu-Delta Opioid Receptor Heteromers Blocks Morphine Rewarding Effects.
Requana Aradas A, Djaboub Y, McCort-Tranchepain I, Hajasova Z, Clémenceau L, Canestrelli C, Mann A, Schulz S, Delaval A, Acher F, Massotte D, Noble F, Marie N. Requana Aradas A, et al. Among authors: mccort tranchepain i. Int J Neuropsychopharmacol. 2023 Jul 31;26(7):513-521. doi: 10.1093/ijnp/pyad032. Int J Neuropsychopharmacol. 2023. PMID: 37343217 Free PMC article.
Increased Potency and Selectivity for Group III Metabotropic Glutamate Receptor Agonists Binding at Dual sites.
Selvam C, Lemasson IA, Brabet I, Oueslati N, Karaman B, Cabaye A, Tora AS, Commare B, Courtiol T, Cesarini S, McCort-Tranchepain I, Rigault D, Mony L, Bessiron T, McLean H, Leroux FR, Colobert F, Daniel H, Goupil-Lamy A, Bertrand HO, Goudet C, Pin JP, Acher FC. Selvam C, et al. Among authors: mccort tranchepain i. J Med Chem. 2018 Mar 8;61(5):1969-1989. doi: 10.1021/acs.jmedchem.7b01438. Epub 2018 Feb 14. J Med Chem. 2018. PMID: 29397723
The mGlu7 receptor provides protective effects against epileptogenesis and epileptic seizures.
Girard B, Tuduri P, Moreno MP, Sakkaki S, Barboux C, Bouschet T, Varrault A, Vitre J, McCort-Tranchepain I, Dairou J, Acher F, Fagni L, Marchi N, Perroy J, Bertaso F. Girard B, et al. Among authors: mccort tranchepain i. Neurobiol Dis. 2019 Sep;129:13-28. doi: 10.1016/j.nbd.2019.04.016. Epub 2019 Apr 30. Neurobiol Dis. 2019. PMID: 31051234
Amino Acids Bearing Aromatic or Heteroaromatic Substituents as a New Class of Ligands for the Lysosomal Sialic Acid Transporter Sialin.
Dubois L, Pietrancosta N, Cabaye A, Fanget I, Debacker C, Gilormini PA, Dansette PM, Dairou J, Biot C, Froissart R, Goupil-Lamy A, Bertrand HO, Acher FC, McCort-Tranchepain I, Gasnier B, Anne C. Dubois L, et al. Among authors: mccort tranchepain i. J Med Chem. 2020 Aug 13;63(15):8231-8249. doi: 10.1021/acs.jmedchem.9b02119. Epub 2020 Jul 15. J Med Chem. 2020. PMID: 32608236 Free article.
Conformational pathway provides unique sensitivity to a synaptic mGluR.
Habrian CH, Levitz J, Vyklicky V, Fu Z, Hoagland A, McCort-Tranchepain I, Acher F, Isacoff EY. Habrian CH, et al. Among authors: mccort tranchepain i. Nat Commun. 2019 Dec 5;10(1):5572. doi: 10.1038/s41467-019-13407-8. Nat Commun. 2019. PMID: 31804469 Free PMC article.
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