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Purinergic GPCR-integrin interactions drive pancreatic cancer cell invasion.
Tomas Bort E, Joseph MD, Wang Q, Carter EP, Roth NJ, Gibson J, Samadi A, Kocher HM, Simoncelli S, McCormick PJ, Grose RP. Tomas Bort E, et al. Among authors: mccormick pj. Elife. 2023 Mar 21;12:e86971. doi: 10.7554/eLife.86971. Elife. 2023. PMID: 36942939 Free PMC article.
Development of High-Specificity Fluorescent Probes to Enable Cannabinoid Type 2 Receptor Studies in Living Cells.
Sarott RC, Westphal MV, Pfaff P, Korn C, Sykes DA, Gazzi T, Brennecke B, Atz K, Weise M, Mostinski Y, Hompluem P, Koers E, Miljuš T, Roth NJ, Asmelash H, Vong MC, Piovesan J, Guba W, Rufer AC, Kusznir EA, Huber S, Raposo C, Zirwes EA, Osterwald A, Pavlovic A, Moes S, Beck J, Benito-Cuesta I, Grande T, Ruiz de Martı N Esteban S, Yeliseev A, Drawnel F, Widmer G, Holzer D, van der Wel T, Mandhair H, Yuan CY, Drobyski WR, Saroz Y, Grimsey N, Honer M, Fingerle J, Gawrisch K, Romero J, Hillard CJ, Varga ZV, van der Stelt M, Pacher P, Gertsch J, McCormick PJ, Ullmer C, Oddi S, Maccarrone M, Veprintsev DB, Nazaré M, Grether U, Carreira EM. Sarott RC, et al. Among authors: mccormick pj. J Am Chem Soc. 2020 Oct 7;142(40):16953-16964. doi: 10.1021/jacs.0c05587. Epub 2020 Sep 29. J Am Chem Soc. 2020. PMID: 32902974
Modulation of dopamine D1 receptors via histamine H3 receptors is a novel therapeutic target for Huntington's disease.
Moreno-Delgado D, Puigdellívol M, Moreno E, Rodríguez-Ruiz M, Botta J, Gasperini P, Chiarlone A, Howell LA, Scarselli M, Casadó V, Cortés A, Ferré S, Guzmán M, Lluís C, Alberch J, Canela EI, Ginés S, McCormick PJ. Moreno-Delgado D, et al. Among authors: mccormick pj. Elife. 2020 Jun 9;9:e51093. doi: 10.7554/eLife.51093. Elife. 2020. PMID: 32513388 Free PMC article.
Detection of cannabinoid receptor type 2 in native cells and zebrafish with a highly potent, cell-permeable fluorescent probe.
Gazzi T, Brennecke B, Atz K, Korn C, Sykes D, Forn-Cuni G, Pfaff P, Sarott RC, Westphal MV, Mostinski Y, Mach L, Wasinska-Kalwa M, Weise M, Hoare BL, Miljuš T, Mexi M, Roth N, Koers EJ, Guba W, Alker A, Rufer AC, Kusznir EA, Huber S, Raposo C, Zirwes EA, Osterwald A, Pavlovic A, Moes S, Beck J, Nettekoven M, Benito-Cuesta I, Grande T, Drawnel F, Widmer G, Holzer D, van der Wel T, Mandhair H, Honer M, Fingerle J, Scheffel J, Broichhagen J, Gawrisch K, Romero J, Hillard CJ, Varga ZV, van der Stelt M, Pacher P, Gertsch J, Ullmer C, McCormick PJ, Oddi S, Spaink HP, Maccarrone M, Veprintsev DB, Carreira EM, Grether U, Nazaré M. Gazzi T, et al. Among authors: mccormick pj. Chem Sci. 2022 Apr 1;13(19):5539-5545. doi: 10.1039/d1sc06659e. eCollection 2022 May 18. Chem Sci. 2022. PMID: 35694350 Free PMC article.
Probing GPCR Dimerization Using Peptides.
Farooq Z, Howell LA, McCormick PJ. Farooq Z, et al. Among authors: mccormick pj. Front Endocrinol (Lausanne). 2022 Jul 14;13:843770. doi: 10.3389/fendo.2022.843770. eCollection 2022. Front Endocrinol (Lausanne). 2022. PMID: 35909575 Free PMC article. Review.
Continuing challenges in targeting oligomeric GPCR-based drugs.
Botta J, Appelhans J, McCormick PJ. Botta J, et al. Among authors: mccormick pj. Prog Mol Biol Transl Sci. 2020;169:213-245. doi: 10.1016/bs.pmbts.2019.11.009. Epub 2020 Jan 3. Prog Mol Biol Transl Sci. 2020. PMID: 31952687 Review.
173 results