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Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition.
Hangauer MJ, Viswanathan VS, Ryan MJ, Bole D, Eaton JK, Matov A, Galeas J, Dhruv HD, Berens ME, Schreiber SL, McCormick F, McManus MT. Hangauer MJ, et al. Among authors: mccormick f. Nature. 2017 Nov 9;551(7679):247-250. doi: 10.1038/nature24297. Epub 2017 Nov 1. Nature. 2017. PMID: 29088702 Free PMC article.
Linking tumor mutations to drug responses via a quantitative chemical-genetic interaction map.
Martins MM, Zhou AY, Corella A, Horiuchi D, Yau C, Rakhshandehroo T, Gordan JD, Levin RS, Johnson J, Jascur J, Shales M, Sorrentino A, Cheah J, Clemons PA, Shamji AF, Schreiber SL, Krogan NJ, Shokat KM, McCormick F, Goga A, Bandyopadhyay S. Martins MM, et al. Among authors: mccormick f. Cancer Discov. 2015 Feb;5(2):154-67. doi: 10.1158/2159-8290.CD-14-0552. Epub 2014 Dec 12. Cancer Discov. 2015. PMID: 25501949 Free PMC article.
Ras-GTP dimers activate the Mitogen-Activated Protein Kinase (MAPK) pathway.
Nan X, Tamgüney TM, Collisson EA, Lin LJ, Pitt C, Galeas J, Lewis S, Gray JW, McCormick F, Chu S. Nan X, et al. Among authors: mccormick f. Proc Natl Acad Sci U S A. 2015 Jun 30;112(26):7996-8001. doi: 10.1073/pnas.1509123112. Epub 2015 Jun 16. Proc Natl Acad Sci U S A. 2015. PMID: 26080442 Free PMC article.
Drug Resistance to EGFR Inhibitors in Lung Cancer.
Tetsu O, Hangauer MJ, Phuchareon J, Eisele DW, McCormick F. Tetsu O, et al. Among authors: mccormick f. Chemotherapy. 2016;61(5):223-35. doi: 10.1159/000443368. Epub 2016 Feb 25. Chemotherapy. 2016. PMID: 26910730 Free PMC article. Review.
591 results