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Dystrophin involvement in peripheral circadian SRF signalling.
Betts CA, Jagannath A, van Westering TL, Bowerman M, Banerjee S, Meng J, Falzarano MS, Cravo L, McClorey G, Meijboom KE, Bhomra A, Lim WF, Rinaldi C, Counsell JR, Chwalenia K, O'Donovan E, Saleh AF, Gait MJ, Morgan JE, Ferlini A, Foster RG, Wood MJ. Betts CA, et al. Among authors: mcclorey g. Life Sci Alliance. 2021 Aug 13;4(10):e202101014. doi: 10.26508/lsa.202101014. Print 2021 Oct. Life Sci Alliance. 2021. PMID: 34389686 Free PMC article.
Cmah-dystrophin deficient mdx mice display an accelerated cardiac phenotype that is improved following peptide-PMO exon skipping treatment.
Betts CA, McClorey G, Healicon R, Hammond SM, Manzano R, Muses S, Ball V, Godfrey C, Merritt TM, van Westering T, O'Donovan L, Wells KE, Gait MJ, Wells DJ, Tyler D, Wood MJ. Betts CA, et al. Among authors: mcclorey g. Hum Mol Genet. 2019 Feb 1;28(3):396-406. doi: 10.1093/hmg/ddy346. Hum Mol Genet. 2019. PMID: 30281092 Free PMC article.
Uniform sarcolemmal dystrophin expression is required to prevent extracellular microRNA release and improve dystrophic pathology.
van Westering TLE, Lomonosova Y, Coenen-Stass AML, Betts CA, Bhomra A, Hulsker M, Clark LE, McClorey G, Aartsma-Rus A, van Putten M, Wood MJA, Roberts TC. van Westering TLE, et al. Among authors: mcclorey g. J Cachexia Sarcopenia Muscle. 2020 Apr;11(2):578-593. doi: 10.1002/jcsm.12506. Epub 2019 Dec 17. J Cachexia Sarcopenia Muscle. 2020. PMID: 31849191 Free PMC article.
Dual Myostatin and Dystrophin Exon Skipping by Morpholino Nucleic Acid Oligomers Conjugated to a Cell-penetrating Peptide Is a Promising Therapeutic Strategy for the Treatment of Duchenne Muscular Dystrophy.
Malerba A, Kang JK, McClorey G, Saleh AF, Popplewell L, Gait MJ, Wood MJ, Dickson G. Malerba A, et al. Among authors: mcclorey g. Mol Ther Nucleic Acids. 2012 Dec 18;1(12):e62. doi: 10.1038/mtna.2012.54. Mol Ther Nucleic Acids. 2012. PMID: 23250360 Free PMC article.
40 results