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SER-109, an Oral Microbiome Therapy for Recurrent Clostridioides difficile Infection.
N Engl J Med. 2022 Jan 20;386(3):220-229. doi: 10.1056/NEJMoa2106516.
N Engl J Med. 2022.
PMID: 35045228
Clinical Trial.
SER-109, an Investigational Microbiome Drug to Reduce Recurrence After Clostridioides difficile Infection: Lessons Learned From a Phase 2 Trial.
McGovern BH, Ford CB, Henn MR, Pardi DS, Khanna S, Hohmann EL, O'Brien EJ, Desjardins CA, Bernardo P, Wortman JR, Lombardo MJ, Litcofsky KD, Winkler JA, McChalicher CWJ, Li SS, Tomlinson AD, Nandakumar M, Cook DN, Pomerantz RJ, Auninš JG, Trucksis M.
McGovern BH, et al. Among authors: mcchalicher cwj.
Clin Infect Dis. 2021 Jun 15;72(12):2132-2140. doi: 10.1093/cid/ciaa387.
Clin Infect Dis. 2021.
PMID: 32255488
Free PMC article.
Clinical Trial.
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SER-109: An Oral Investigational Microbiome Therapeutic for Patients with Recurrent Clostridioides difficile Infection (rCDI).
Khanna S, Sims M, Louie TJ, Fischer M, LaPlante K, Allegretti J, Hasson BR, Fonte AT, McChalicher C, Ege DS, Bryant JA, Straub TJ, Ford CB, Henn MR, Wang EEL, von Moltke L, Wilcox MH.
Khanna S, et al.
Antibiotics (Basel). 2022 Sep 10;11(9):1234. doi: 10.3390/antibiotics11091234.
Antibiotics (Basel). 2022.
PMID: 36140013
Free PMC article.
Review.
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Manufacturing Process of SER-109, a Purified Investigational Microbiome Therapeutic, Reduces Risk of Coronavirus Transmission From Donor Stool.
McChalicher C, Abdulaziz A, Zhou SS, Lombardo MJ, Hasson B, Auniņš JG, McGovern BH, Ege DS.
McChalicher C, et al.
Open Forum Infect Dis. 2022 Sep 2;9(9):ofac448. doi: 10.1093/ofid/ofac448. eCollection 2022 Sep.
Open Forum Infect Dis. 2022.
PMID: 36158136
Free PMC article.
Item in Clipboard
Drugging the microbiome and bacterial live biotherapeutic consortium production.
McChalicher CW, Auniņš JG.
McChalicher CW, et al.
Curr Opin Biotechnol. 2022 Dec;78:102801. doi: 10.1016/j.copbio.2022.102801. Epub 2022 Oct 10.
Curr Opin Biotechnol. 2022.
PMID: 36228531
Free article.
Review.
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Manufacturing Processes of a Purified Microbiome Therapeutic Reduce Risk of Transmission of Potential Bacterial Pathogens in Donor Stool.
McChalicher CWJ, Lombardo MJ, Khanna S, McKenzie GJ, Halvorsen EM, Almomani S, Schuster B, Hasson BR, McGovern BH, Ege DS, Auniņš JG.
McChalicher CWJ, et al.
J Infect Dis. 2023 Nov 11;228(10):1452-1455. doi: 10.1093/infdis/jiad298.
J Infect Dis. 2023.
PMID: 37540090
Free PMC article.
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Investigating the structure-property relationship of bacterial PHA block copolymers.
McChalicher CW, Srienc F.
McChalicher CW, et al.
J Biotechnol. 2007 Nov 1;132(3):296-302. doi: 10.1016/j.jbiotec.2007.04.014. Epub 2007 Apr 29.
J Biotechnol. 2007.
PMID: 17566581
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Bacterial synthesis of PHA block copolymers.
Pederson EN, McChalicher CW, Srienc F.
Pederson EN, et al.
Biomacromolecules. 2006 Jun;7(6):1904-11. doi: 10.1021/bm0510101.
Biomacromolecules. 2006.
PMID: 16768413
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