McCarthy SG - Search Results

1

Functional, Biophysical, and Structural Characterization of Human IgG1 and IgG4 Fc Variants with Ablated Immune Functionality.

Tam SH, McCarthy SG, Armstrong AA, Somani S, Wu SJ, Liu X, Gervais A, Ernst R, Saro D, Decker R, Luo J, Gilliland GL, Chiu ML, Scallon BJ. Tam SH, et al. Among authors: mccarthy sg. Antibodies (Basel). 2017 Sep 1;6(3):12. doi: 10.3390/antib6030012. Antibodies (Basel). 2017. PMID: 31548527 Free PMC article.

2

Higher levels of sialylated Fc glycans in immunoglobulin G molecules can adversely impact functionality.

Scallon BJ, Tam SH, McCarthy SG, Cai AN, Raju TS. Scallon BJ, et al. Among authors: mccarthy sg. Mol Immunol. 2007 Mar;44(7):1524-34. doi: 10.1016/j.molimm.2006.09.005. Epub 2006 Oct 11. Mol Immunol. 2007. PMID: 17045339

3

Quantitative in vivo comparisons of the Fc gamma receptor-dependent agonist activities of different fucosylation variants of an immunoglobulin G antibody.

Scallon B, McCarthy S, Radewonuk J, Cai A, Naso M, Raju TS, Capocasale R. Scallon B, et al. Int Immunopharmacol. 2007 Jun;7(6):761-72. doi: 10.1016/j.intimp.2007.01.014. Epub 2007 Feb 15. Int Immunopharmacol. 2007. PMID: 17466910

4

Correlations between pharmacokinetics of IgG antibodies in primates vs. FcRn-transgenic mice reveal a rodent model with predictive capabilities.

Tam SH, McCarthy SG, Brosnan K, Goldberg KM, Scallon BJ. Tam SH, et al. Among authors: mccarthy sg. MAbs. 2013 May-Jun;5(3):397-405. doi: 10.4161/mabs.23836. Epub 2013 Apr 2. MAbs. 2013. PMID: 23549129 Free PMC article.

5

Functional optimization of agonistic antibodies to OX40 receptor with novel Fc mutations to promote antibody multimerization.

Zhang D, Armstrong AA, Tam SH, McCarthy SG, Luo J, Gilliland GL, Chiu ML. Zhang D, et al. Among authors: mccarthy sg. MAbs. 2017 Oct;9(7):1129-1142. doi: 10.1080/19420862.2017.1358838. Epub 2017 Jul 31. MAbs. 2017. PMID: 28758875 Free PMC article.

6

Multivalent human antibody-centyrin fusion protein to prevent and treat Staphylococcus aureus infections.

Buckley PT, Chan R, Fernandez J, Luo J, Lacey KA, DuMont AL, O'Malley A, Brezski RJ, Zheng S, Malia T, Whitaker B, Zwolak A, Payne A, Clark D, Sigg M, Lacy ER, Kornilova A, Kwok D, McCarthy S, Wu B, Morrow B, Nemeth-Seay J, Petley T, Wu S, Strohl WR, Lynch AS, Torres VJ. Buckley PT, et al. Cell Host Microbe. 2023 May 10;31(5):751-765.e11. doi: 10.1016/j.chom.2023.04.004. Epub 2023 Apr 24. Cell Host Microbe. 2023. PMID: 37098341 Free article.

7

Engineered protease-resistant antibodies with selectable cell-killing functions.

Kinder M, Greenplate AR, Grugan KD, Soring KL, Heeringa KA, McCarthy SG, Bannish G, Perpetua M, Lynch F, Jordan RE, Strohl WR, Brezski RJ. Kinder M, et al. Among authors: mccarthy sg. J Biol Chem. 2013 Oct 25;288(43):30843-54. doi: 10.1074/jbc.M113.486142. Epub 2013 Aug 28. J Biol Chem. 2013. PMID: 23986451 Free PMC article.

8

Induction of Th1-type immunity and tumor protection with a prostate-specific antigen DNA vaccine.

Marshall DJ, San Mateo LR, Rudnick KA, McCarthy SG, Harris MC, McCauley C, Schantz A, Geng D, Cawood P, Snyder LA. Marshall DJ, et al. Among authors: mccarthy sg. Cancer Immunol Immunother. 2005 Nov;54(11):1082-94. doi: 10.1007/s00262-005-0687-0. Epub 2005 Jul 27. Cancer Immunol Immunother. 2005. PMID: 16047142 Free PMC article.

9

Engineering human IL-18 with increased bioactivity and bioavailability.

Swencki-Underwood B, Cunningham MR, Heavner GA, Blasie C, McCarthy SG, Dougherty T, Brigham-Burke M, Gunn GR, Goletz TJ, Snyder LA. Swencki-Underwood B, et al. Among authors: mccarthy sg. Cytokine. 2006 Apr;34(1-2):114-24. doi: 10.1016/j.cyto.2006.04.004. Cytokine. 2006. PMID: 16750378

10

Interleukin-18 enhances Th1 immunity and tumor protection of a DNA vaccine.

Marshall DJ, Rudnick KA, McCarthy SG, Mateo LR, Harris MC, McCauley C, Snyder LA. Marshall DJ, et al. Among authors: mccarthy sg. Vaccine. 2006 Jan 16;24(3):244-53. doi: 10.1016/j.vaccine.2005.07.087. Epub 2005 Aug 15. Vaccine. 2006. PMID: 16135392

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