McBrayer T - Search Results

1

Synthesis and biological evaluation of novel peptidomimetic inhibitors of the coronavirus 3C-like protease.

Amblard F, LeCher JC, De R, Zhou S, Liu P, Goh SL, Tao S, Patel D, Downs-Bowen J, Zandi K, Zhang H, Chaudhry G, McBrayer T, Muczynski M, Al-Homoudi A, Engel J, Lan S, Sarafianos SG, Kovari LC, Schinazi RF. Amblard F, et al. Among authors: mcbrayer t. Eur J Med Chem. 2024 Mar 15;268:116263. doi: 10.1016/j.ejmech.2024.116263. Epub 2024 Feb 24. Eur J Med Chem. 2024. PMID: 38432056

2

Synthesis of N3,5'-cyclo-4-(beta-D-ribofuranosyl)-vic-triazolo[4,5-b]pyridin-5-one, a novel compound with anti-hepatitis C virus activity.

Wang P, Hollecker L, Pankiewicz KW, Patterson SE, Whitaker T, McBrayer TR, Tharnish PM, Sidwell RW, Stuyver LJ, Otto MJ, Schinazi RF, Watanabe KA. Wang P, et al. Among authors: mcbrayer tr. J Med Chem. 2004 Nov 18;47(24):6100-3. doi: 10.1021/jm0401210. J Med Chem. 2004. PMID: 15537363

3

Synthesis and anti-viral activity of a series of d- and l-2'-deoxy-2'-fluororibonucleosides in the subgenomic HCV replicon system.

Shi J, Du J, Ma T, Pankiewicz KW, Patterson SE, Tharnish PM, McBrayer TR, Stuyver LJ, Otto MJ, Chu CK, Schinazi RF, Watanabe KA. Shi J, et al. Among authors: mcbrayer tr. Bioorg Med Chem. 2005 Mar 1;13(5):1641-52. doi: 10.1016/j.bmc.2004.12.011. Bioorg Med Chem. 2005. PMID: 15698782

4

Design, synthesis, and antiviral activity of 2'-deoxy-2'-fluoro-2'-C-methylcytidine, a potent inhibitor of hepatitis C virus replication.

Clark JL, Hollecker L, Mason JC, Stuyver LJ, Tharnish PM, Lostia S, McBrayer TR, Schinazi RF, Watanabe KA, Otto MJ, Furman PA, Stec WJ, Patterson SE, Pankiewicz KW. Clark JL, et al. J Med Chem. 2005 Aug 25;48(17):5504-8. doi: 10.1021/jm0502788. J Med Chem. 2005. PMID: 16107149

5

Synthesis and antiviral activity of 2'-deoxy-2'-fluoro-2'-C-methyl purine nucleosides as inhibitors of hepatitis C virus RNA replication.

Clark JL, Mason JC, Hollecker L, Stuyver LJ, Tharnish PM, McBrayer TR, Otto MJ, Furman PA, Schinazi RF, Watanabe KA. Clark JL, et al. Bioorg Med Chem Lett. 2006 Mar 15;16(6):1712-5. doi: 10.1016/j.bmcl.2005.12.002. Epub 2005 Dec 20. Bioorg Med Chem Lett. 2006. PMID: 16368235

6

Synthesis, antiviral activity, and stability of nucleoside analogs containing tricyclic bases.

Amblard F, Fromentin E, Detorio M, Obikhod A, Rapp KL, McBrayer TR, Whitaker T, Coats SJ, Schinazi RF. Amblard F, et al. Among authors: mcbrayer tr. Eur J Med Chem. 2009 Oct;44(10):3845-51. doi: 10.1016/j.ejmech.2009.04.003. Epub 2009 Apr 8. Eur J Med Chem. 2009. PMID: 19433343 Free PMC article.

7

Anti-hepatitis C virus activity of novel beta-d-2'-C-methyl-4'-azido pyrimidine nucleoside phosphoramidate prodrugs.

Rondla R, Coats SJ, McBrayer TR, Grier J, Johns M, Tharnish PM, Whitaker T, Zhou L, Schinazi RF. Rondla R, et al. Among authors: mcbrayer tr. Antivir Chem Chemother. 2009 Oct 19;20(2):99-106. doi: 10.3851/IMP1400. Antivir Chem Chemother. 2009. PMID: 19843980 Free PMC article.

8

3'-(1,2,3-Triazol-1-yl)-3'-deoxythymidine analogs as substrates for human and Ureaplasma parvum thymidine kinase for structure-activity investigations.

Lin J, Roy V, Wang L, You L, Agrofoglio LA, Deville-Bonne D, McBrayer TR, Coats SJ, Schinazi RF, Eriksson S. Lin J, et al. Bioorg Med Chem. 2010 May 1;18(9):3261-9. doi: 10.1016/j.bmc.2010.03.023. Epub 2010 Mar 15. Bioorg Med Chem. 2010. PMID: 20378362 Free PMC article.

9

Synthesis of purine modified 2'-C-methyl nucleosides as potential anti-HCV agents.

Zhang HW, Zhou L, Coats SJ, McBrayer TR, Tharnish PM, Bondada L, Detorio M, Amichai SA, Johns MD, Whitaker T, Schinazi RF. Zhang HW, et al. Among authors: mcbrayer tr. Bioorg Med Chem Lett. 2011 Nov 15;21(22):6788-92. doi: 10.1016/j.bmcl.2011.09.034. Epub 2011 Sep 20. Bioorg Med Chem Lett. 2011. PMID: 21983447 Free PMC article.

10

Synthesis and antiviral activity of 2'-deoxy-2'-fluoro-2'-C-methyl-7-deazapurine nucleosides, their phosphoramidate prodrugs and 5'-triphosphates.

Shi J, Zhou L, Zhang H, McBrayer TR, Detorio MA, Johns M, Bassit L, Powdrill MH, Whitaker T, Coats SJ, Götte M, Schinazi RF. Shi J, et al. Among authors: mcbrayer tr. Bioorg Med Chem Lett. 2011 Dec 1;21(23):7094-8. doi: 10.1016/j.bmcl.2011.09.089. Epub 2011 Sep 29. Bioorg Med Chem Lett. 2011. PMID: 22014549 Free PMC article.

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