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The Notch pathway regulates the bone gain induced by PTH anabolic signaling.
Delgado-Calle J, McAndrews K, Wu G, Orr AL, Ferrari A, Tu X, Srinivasan V, Roodman GD, Ebetino FH, Boeckman RK Jr, Bellido T. Delgado-Calle J, et al. Among authors: mcandrews k. FASEB J. 2022 Mar;36(3):e22196. doi: 10.1096/fj.202101807R. FASEB J. 2022. PMID: 35137455 Free PMC article.
Control of Bone Anabolism in Response to Mechanical Loading and PTH by Distinct Mechanisms Downstream of the PTH Receptor.
Delgado-Calle J, Tu X, Pacheco-Costa R, McAndrews K, Edwards R, Pellegrini GG, Kuhlenschmidt K, Olivos N, Robling A, Peacock M, Plotkin LI, Bellido T. Delgado-Calle J, et al. Among authors: mcandrews k. J Bone Miner Res. 2017 Mar;32(3):522-535. doi: 10.1002/jbmr.3011. Epub 2016 Oct 27. J Bone Miner Res. 2017. PMID: 27704638 Free PMC article.
MMP14 is a novel target of PTH signaling in osteocytes that controls resorption by regulating soluble RANKL production.
Delgado-Calle J, Hancock B, Likine EF, Sato AY, McAndrews K, Sanudo C, Bruzzaniti A, Riancho JA, Tonra JR, Bellido T. Delgado-Calle J, et al. Among authors: mcandrews k. FASEB J. 2018 May;32(5):2878-2890. doi: 10.1096/fj.201700919RRR. Epub 2018 Jan 17. FASEB J. 2018. PMID: 29401593 Free PMC article.
-Delgado-Calle, J., Hancock, B., Likine, E. F., Sato, A. Y., McAndrews, K., Sanudo, C., Bruzzaniti, A., Riancho, J. A., Tonra, J. ...
-Delgado-Calle, J., Hancock, B., Likine, E. F., Sato, A. Y., McAndrews, K., Sanudo, C., Bruzzaniti, A., Riancho, J. A., Tonra, …
Skeletal Protection and Promotion of Microbiome Diversity by Dietary Boosting of the Endogenous Antioxidant Response.
Sato AY, Pellegrini GG, Cregor M, McAndrews K, Choi RB, Maiz M, Johnson O, McCabe LD, McCabe GP, Ferruzzi MG, Lila MA, Peacock M, Burr DB, Nakatsu CH, Weaver CM, Bellido T. Sato AY, et al. Among authors: mcandrews k. J Bone Miner Res. 2021 Apr;36(4):768-778. doi: 10.1002/jbmr.4231. Epub 2020 Dec 30. J Bone Miner Res. 2021. PMID: 33316081 Free article.
Targeting Notch Inhibitors to the Myeloma Bone Marrow Niche Decreases Tumor Growth and Bone Destruction without Gut Toxicity.
Sabol HM, Ferrari AJ, Adhikari M, Amorim T, McAndrews K, Anderson J, Vigolo M, Lehal R, Cregor M, Khan S, Cuevas PL, Helms JA, Kurihara N, Srinivasan V, Ebetino FH, Boeckman RK Jr, Roodman GD, Bellido T, Delgado-Calle J. Sabol HM, et al. Among authors: mcandrews k. Cancer Res. 2021 Oct 1;81(19):5102-5114. doi: 10.1158/0008-5472.CAN-21-0524. Epub 2021 Aug 4. Cancer Res. 2021. PMID: 34348968 Free PMC article.
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