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A Review of ex vivo Elemental Mapping Methods to Directly Image Changes in the Homeostasis of Diffusible Ions (Na+, K+, Mg2 +, Ca2 +, Cl-) Within Brain Tissue.
Hartnell D, Andrews W, Smith N, Jiang H, McAllum E, Rajan R, Colbourne F, Fitzgerald M, Lam V, Takechi R, Pushie MJ, Kelly ME, Hackett MJ. Hartnell D, et al. Among authors: mcallum e. Front Neurosci. 2020 Jan 22;13:1415. doi: 10.3389/fnins.2019.01415. eCollection 2019. Front Neurosci. 2020. PMID: 32038130 Free PMC article. Review.
Oral treatment with Cu(II)(atsm) increases mutant SOD1 in vivo but protects motor neurons and improves the phenotype of a transgenic mouse model of amyotrophic lateral sclerosis.
Roberts BR, Lim NK, McAllum EJ, Donnelly PS, Hare DJ, Doble PA, Turner BJ, Price KA, Lim SC, Paterson BM, Hickey JL, Rhoads TW, Williams JR, Kanninen KM, Hung LW, Liddell JR, Grubman A, Monty JF, Llanos RM, Kramer DR, Mercer JF, Bush AI, Masters CL, Duce JA, Li QX, Beckman JS, Barnham KJ, White AR, Crouch PJ. Roberts BR, et al. Among authors: mcallum ej. J Neurosci. 2014 Jun 4;34(23):8021-31. doi: 10.1523/JNEUROSCI.4196-13.2014. J Neurosci. 2014. PMID: 24899723 Free PMC article.
Copper delivery to the CNS by CuATSM effectively treats motor neuron disease in SOD(G93A) mice co-expressing the Copper-Chaperone-for-SOD.
Williams JR, Trias E, Beilby PR, Lopez NI, Labut EM, Bradford CS, Roberts BR, McAllum EJ, Crouch PJ, Rhoads TW, Pereira C, Son M, Elliott JL, Franco MC, Estévez AG, Barbeito L, Beckman JS. Williams JR, et al. Among authors: mcallum ej. Neurobiol Dis. 2016 May;89:1-9. doi: 10.1016/j.nbd.2016.01.020. Epub 2016 Jan 27. Neurobiol Dis. 2016. PMID: 26826269 Free PMC article.
Neonatal iron supplementation potentiates oxidative stress, energetic dysfunction and neurodegeneration in the R6/2 mouse model of Huntington's disease.
Berggren KL, Chen J, Fox J, Miller J, Dodds L, Dugas B, Vargas L, Lothian A, McAllum E, Volitakis I, Roberts B, Bush AI, Fox JH. Berggren KL, et al. Among authors: mcallum e. Redox Biol. 2015;4:363-74. doi: 10.1016/j.redox.2015.02.002. Epub 2015 Feb 11. Redox Biol. 2015. PMID: 25703232 Free PMC article.