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Discovery of small molecules that target a tertiary-structured RNA.
Menichelli E, Lam BJ, Wang Y, Wang VS, Shaffer J, Tjhung KF, Bursulaya B, Nguyen TN, Vo T, Alper PB, McAllister CS, Jones DH, Spraggon G, Michellys PY, Joslin J, Joyce GF, Rogers J. Menichelli E, et al. Among authors: mcallister cs. Proc Natl Acad Sci U S A. 2022 Nov 29;119(48):e2213117119. doi: 10.1073/pnas.2213117119. Epub 2022 Nov 21. Proc Natl Acad Sci U S A. 2022. PMID: 36413497 Free PMC article.
Dexamethasone inhibits respiratory syncytial virus-driven mucus production while increasing viral replication without altering antiviral interferon signaling.
McAllister CS, Ansaldi D, Growcott EJ, Zhong Y, Quackenbush D, Wolff KC, Chen Z, Tanaseichuk O, Lelais G, Barnes SW, Federe GC, Luna F, Walker JR, Zhou Y, Kuhen KL. McAllister CS, et al. Virology. 2020 Jan 15;540:195-206. doi: 10.1016/j.virol.2019.10.007. Epub 2019 Oct 23. Virology. 2020. PMID: 31929001 Free article.
TLR3 signaling is downregulated by a MAVS isoform in epithelial cells.
Lakhdari O, McAllister CS, Wang M, Minev I, Prince LS, Eckmann L, Kagnoff MF. Lakhdari O, et al. Among authors: mcallister cs. Cell Immunol. 2016 Dec;310:205-210. doi: 10.1016/j.cellimm.2016.08.010. Epub 2016 Aug 24. Cell Immunol. 2016. PMID: 27593154 Free PMC article.
15 results