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Repurposing Study of 4-Acyl-1-phenylaminocarbonyl-2-substituted-piperazine Derivatives as Potential Anticancer Agents-In Vitro Evaluation against Breast Cancer Cells.
Guillén-Mancina E, García-Lozano MDR, Burgos-Morón E, Mazzotta S, Martínez-Aguado P, Calderón-Montaño JM, Vega-Pérez JM, López-Lázaro M, Iglesias-Guerra F, Vega-Holm M. Guillén-Mancina E, et al. Among authors: mazzotta s. Int J Mol Sci. 2023 Dec 1;24(23):17041. doi: 10.3390/ijms242317041. Int J Mol Sci. 2023. PMID: 38069364 Free PMC article.
Optimization of piperazine-derived ureas privileged structures for effective antiadenovirus agents.
Mazzotta S, Marrugal-Lorenzo JA, Vega-Holm M, Serna-Gallego A, Álvarez-Vidal J, Berastegui-Cabrera J, Pérez Del Palacio J, Díaz C, Aiello F, Pachón J, Iglesias-Guerra F, Vega-Pérez JM, Sánchez-Céspedes J. Mazzotta S, et al. Eur J Med Chem. 2020 Jan 1;185:111840. doi: 10.1016/j.ejmech.2019.111840. Epub 2019 Nov 3. Eur J Med Chem. 2020. PMID: 31711794
Exploration of piperazine-derived thioureas as antibacterial and anti-inflammatory agents. In vitro evaluation against clinical isolates of colistin-resistant Acinetobacter baumannii.
Mazzotta S, Cebrero-Cangueiro T, Frattaruolo L, Vega-Holm M, Carretero-Ledesma M, Sánchez-Céspedes J, Cappello AR, Aiello F, Pachón J, Vega-Pérez JM, Iglesias-Guerra F, Pachón-Ibáñez ME. Mazzotta S, et al. Bioorg Med Chem Lett. 2020 Sep 15;30(18):127411. doi: 10.1016/j.bmcl.2020.127411. Epub 2020 Jul 15. Bioorg Med Chem Lett. 2020. PMID: 32717617
Serinol-Based Benzoic Acid Esters as New Scaffolds for the Development of Adenovirus Infection Inhibitors: Design, Synthesis, and In Vitro Biological Evaluation.
Mazzotta S, Berastegui-Cabrera J, Carullo G, Vega-Holm M, Carretero-Ledesma M, Mendolia L, Aiello F, Iglesias-Guerra F, Pachón J, Vega-Pérez JM, Sánchez-Céspedes J. Mazzotta S, et al. ACS Infect Dis. 2021 Jun 11;7(6):1433-1444. doi: 10.1021/acsinfecdis.0c00515. Epub 2020 Oct 19. ACS Infect Dis. 2021. PMID: 33073569
Piperazine-derived small molecules as potential Flaviviridae NS3 protease inhibitors. In vitro antiviral activity evaluation against Zika and Dengue viruses.
Del Rosario García-Lozano M, Dragoni F, Gallego P, Mazzotta S, López-Gómez A, Boccuto A, Martínez-Cortés C, Rodríguez-Martínez A, Pérez-Sánchez H, Manuel Vega-Pérez J, Antonio Del Campo J, Vicenti I, Vega-Holm M, Iglesias-Guerra F. Del Rosario García-Lozano M, et al. Among authors: mazzotta s. Bioorg Chem. 2023 Apr;133:106408. doi: 10.1016/j.bioorg.2023.106408. Epub 2023 Feb 4. Bioorg Chem. 2023. PMID: 36801791 Free article.
68 results