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HRG inhibits tumor growth and metastasis by inducing macrophage polarization and vessel normalization through downregulation of PlGF.
Rolny C, Mazzone M, Tugues S, Laoui D, Johansson I, Coulon C, Squadrito ML, Segura I, Li X, Knevels E, Costa S, Vinckier S, Dresselaer T, Åkerud P, De Mol M, Salomäki H, Phillipson M, Wyns S, Larsson E, Buysschaert I, Botling J, Himmelreich U, Van Ginderachter JA, De Palma M, Dewerchin M, Claesson-Welsh L, Carmeliet P. Rolny C, et al. Among authors: mazzone m. Cancer Cell. 2011 Jan 18;19(1):31-44. doi: 10.1016/j.ccr.2010.11.009. Epub 2011 Jan 6. Cancer Cell. 2011. PMID: 21215706 Free article.
Tumor hypoxia does not drive differentiation of tumor-associated macrophages but rather fine-tunes the M2-like macrophage population.
Laoui D, Van Overmeire E, Di Conza G, Aldeni C, Keirsse J, Morias Y, Movahedi K, Houbracken I, Schouppe E, Elkrim Y, Karroum O, Jordan B, Carmeliet P, Gysemans C, De Baetselier P, Mazzone M, Van Ginderachter JA. Laoui D, et al. Among authors: mazzone m. Cancer Res. 2014 Jan 1;74(1):24-30. doi: 10.1158/0008-5472.CAN-13-1196. Epub 2013 Nov 12. Cancer Res. 2014. PMID: 24220244
MIF-Mediated Hemodilution Promotes Pathogenic Anemia in Experimental African Trypanosomosis.
Stijlemans B, Brys L, Korf H, Bieniasz-Krzywiec P, Sparkes A, Vansintjan L, Leng L, Vanbekbergen N, Mazzone M, Caljon G, Van Den Abbeele J, Odongo S, De Trez C, Magez S, Van Ginderachter JA, Beschin A, Bucala R, De Baetselier P. Stijlemans B, et al. Among authors: mazzone m. PLoS Pathog. 2016 Sep 15;12(9):e1005862. doi: 10.1371/journal.ppat.1005862. eCollection 2016 Sep. PLoS Pathog. 2016. PMID: 27632207 Free PMC article.
The tumour microenvironment harbours ontogenically distinct dendritic cell populations with opposing effects on tumour immunity.
Laoui D, Keirsse J, Morias Y, Van Overmeire E, Geeraerts X, Elkrim Y, Kiss M, Bolli E, Lahmar Q, Sichien D, Serneels J, Scott CL, Boon L, De Baetselier P, Mazzone M, Guilliams M, Van Ginderachter JA. Laoui D, et al. Among authors: mazzone m. Nat Commun. 2016 Dec 23;7:13720. doi: 10.1038/ncomms13720. Nat Commun. 2016. PMID: 28008905 Free PMC article.
Metabolism and TAM functions-it takes two to tango.
Mazzone M, Menga A, Castegna A. Mazzone M, et al. FEBS J. 2018 Feb;285(4):700-716. doi: 10.1111/febs.14295. Epub 2017 Nov 8. FEBS J. 2018. PMID: 29055087 Free article. Review.
Neutrophils enhance early Trypanosoma brucei infection onset.
Caljon G, Mabille D, Stijlemans B, De Trez C, Mazzone M, Tacchini-Cottier F, Malissen M, Van Ginderachter JA, Magez S, De Baetselier P, Van Den Abbeele J. Caljon G, et al. Among authors: mazzone m. Sci Rep. 2018 Jul 25;8(1):11203. doi: 10.1038/s41598-018-29527-y. Sci Rep. 2018. PMID: 30046157 Free PMC article.
Tumor-associated macrophages: a short compendium.
Prenen H, Mazzone M. Prenen H, et al. Among authors: mazzone m. Cell Mol Life Sci. 2019 Apr;76(8):1447-1458. doi: 10.1007/s00018-018-2997-3. Epub 2019 Feb 12. Cell Mol Life Sci. 2019. PMID: 30747250 Review.
282 results