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New antiplasmodial 4-amino-thieno[3,2-d]pyrimidines with improved intestinal permeability and microsomal stability.
Lagardère P, Mustière R, Amanzougaghene N, Hutter S, Casanova M, Franetich JF, Tajeri S, Malzert-Fréon A, Corvaisier S, Azas N, Vanelle P, Verhaeghe P, Primas N, Mazier D, Masurier N, Lisowski V. Lagardère P, et al. Among authors: mazier d. Eur J Med Chem. 2023 Mar 5;249:115115. doi: 10.1016/j.ejmech.2023.115115. Epub 2023 Jan 13. Eur J Med Chem. 2023. PMID: 36680984
Novel thienopyrimidones targeting hepatic and erythrocytic stages of Plasmodium parasites with increased microsomal stability.
Lagardère P, Mustière R, Amanzougaghene N, Hutter S, Casanova M, Franetich JF, Tajeri S, Malzert-Fréon A, Corvaisier S, Since M, Azas N, Vanelle P, Verhaeghe P, Primas N, Mazier D, Masurier N, Lisowski V. Lagardère P, et al. Among authors: mazier d. Eur J Med Chem. 2023 Dec 5;261:115873. doi: 10.1016/j.ejmech.2023.115873. Epub 2023 Oct 13. Eur J Med Chem. 2023. PMID: 37857143
Azithromycin disrupts apicoplast biogenesis in replicating and dormant liver stages of the relapsing malaria parasites Plasmodium vivax and Plasmodium cynomolgi.
Amanzougaghene N, Tajeri S, Franetich JF, Ashraf K, Soulard V, Bigeard P, Guindo CO, Bouillier C, Lemaitre J, Relouzat F, Legrand R, Kocken CHM, Zeeman AM, Roobsoong W, Sattabongkot J, Yang Z, Snounou G, Mazier D. Amanzougaghene N, et al. Among authors: mazier d. Int J Antimicrob Agents. 2024 May;63(5):107112. doi: 10.1016/j.ijantimicag.2024.107112. Epub 2024 Feb 15. Int J Antimicrob Agents. 2024. PMID: 38367843 Free article.
Rapid and Specific Action of Methylene Blue against Plasmodium Transmission Stages.
Saison N, Franetich JF, Pinilla YT, Hoffmann A, Boussougou-Sambe ST, Ngossanga B, Tefit M, Ashraf K, Amanzougaghene N, Tajeri S, Adegnika AA, Mazier D, Borrmann S. Saison N, et al. Among authors: mazier d. Pharmaceutics. 2022 Dec 14;14(12):2794. doi: 10.3390/pharmaceutics14122794. Pharmaceutics. 2022. PMID: 36559287 Free PMC article.
Application of a low-cost, specific, and sensitive loop-mediated isothermal amplification (LAMP) assay to detect Plasmodium falciparum imported from Africa.
Zhang J, Chen X, Pan M, Qin Y, Zhao H, Yang Q, Li X, Zeng W, Xiang Z, Wu Y, Duan M, Li X, Wang X, Mazier D, Zhang Y, Zhu W, Sun K, Wu Y, Cui L, Huang Y, Yang Z. Zhang J, et al. Among authors: mazier d. Mol Biochem Parasitol. 2022 Nov;252:111529. doi: 10.1016/j.molbiopara.2022.111529. Epub 2022 Oct 29. Mol Biochem Parasitol. 2022. PMID: 36374724 Free PMC article.
4-Substituted Thieno[3,2-d]pyrimidines as Dual-Stage Antiplasmodial Derivatives.
Lagardère P, Mustière R, Amanzougaghene N, Hutter S, Franetich JF, Azas N, Vanelle P, Verhaeghe P, Primas N, Mazier D, Masurier N, Lisowski V. Lagardère P, et al. Among authors: mazier d. Pharmaceuticals (Basel). 2022 Jul 1;15(7):820. doi: 10.3390/ph15070820. Pharmaceuticals (Basel). 2022. PMID: 35890119 Free PMC article.
Synthesis of antiplasmodial 2-aminothieno[3,2-d]pyrimidin-4(3H)-one analogues using the scaffold hopping strategy.
Mustière R, Lagardère P, Hutter S, Dell'Orco V, Amanzougaghene N, Tajeri S, Franetich JF, Corvaisier S, Since M, Malzert-Fréon A, Masurier N, Lisowski V, Verhaeghe P, Mazier D, Azas N, Vanelle P, Primas N. Mustière R, et al. Among authors: mazier d. Eur J Med Chem. 2022 Nov 5;241:114619. doi: 10.1016/j.ejmech.2022.114619. Epub 2022 Jul 20. Eur J Med Chem. 2022. PMID: 35872545
Pd-catalyzed C-C and C-N cross-coupling reactions in 2-aminothieno[3,2-d]pyrimidin-4(3H)-one series for antiplasmodial pharmacomodulation.
Mustière R, Lagardère P, Hutter S, Deraeve C, Schwalen F, Amrane D, Masurier N, Azas N, Lisowski V, Verhaeghe P, Mazier D, Vanelle P, Primas N. Mustière R, et al. Among authors: mazier d. RSC Adv. 2022 Jul 8;12(31):20004-20021. doi: 10.1039/d2ra01687g. eCollection 2022 Jul 6. RSC Adv. 2022. PMID: 35865200 Free PMC article.
281 results