Mazcko CN - Search Results

1

Defining the Value of a Comparative Approach to Cancer Drug Development.

LeBlanc AK, Mazcko CN, Khanna C. LeBlanc AK, et al. Among authors: mazcko cn. Clin Cancer Res. 2016 May 1;22(9):2133-8. doi: 10.1158/1078-0432.CCR-15-2347. Epub 2015 Dec 28. Clin Cancer Res. 2016. PMID: 26712689 Free PMC article. Review.

2

Launching a novel preclinical infrastructure: comparative oncology trials consortium directed therapeutic targeting of TNFalpha to cancer vasculature.

Paoloni MC, Tandle A, Mazcko C, Hanna E, Kachala S, Leblanc A, Newman S, Vail D, Henry C, Thamm D, Sorenmo K, Hajitou A, Pasqualini R, Arap W, Khanna C, Libutti SK. Paoloni MC, et al. PLoS One. 2009;4(3):e4972. doi: 10.1371/journal.pone.0004972. Epub 2009 Mar 30. PLoS One. 2009. PMID: 19330034 Free PMC article. Clinical Trial.

3

Guiding the optimal translation of new cancer treatments from canine to human cancer patients.

Khanna C, London C, Vail D, Mazcko C, Hirschfeld S. Khanna C, et al. Clin Cancer Res. 2009 Sep 15;15(18):5671-7. doi: 10.1158/1078-0432.CCR-09-0719. Epub 2009 Sep 8. Clin Cancer Res. 2009. PMID: 19737961 Free PMC article.

4

The Comparative Oncology Trials Consortium: using spontaneously occurring cancers in dogs to inform the cancer drug development pathway.

Gordon I, Paoloni M, Mazcko C, Khanna C. Gordon I, et al. PLoS Med. 2009 Oct;6(10):e1000161. doi: 10.1371/journal.pmed.1000161. Epub 2009 Oct 13. PLoS Med. 2009. PMID: 19823573 Free PMC article. Review.

5

Rapamycin pharmacokinetic and pharmacodynamic relationships in osteosarcoma: a comparative oncology study in dogs.

Paoloni MC, Mazcko C, Fox E, Fan T, Lana S, Kisseberth W, Vail DM, Nuckolls K, Osborne T, Yalkowsy S, Gustafson D, Yu Y, Cao L, Khanna C. Paoloni MC, et al. PLoS One. 2010 Jun 8;5(6):e11013. doi: 10.1371/journal.pone.0011013. PLoS One. 2010. PMID: 20543980 Free PMC article.

6

The creation of the Comparative Oncology Trials Consortium Pharmacodynamic Core: Infrastructure for a virtual laboratory.

Paoloni M, Lana S, Thamm D, Mazcko C, Withrow S. Paoloni M, et al. Vet J. 2010 Jul;185(1):88-9. doi: 10.1016/j.tvjl.2010.04.019. Epub 2010 Jun 2. Vet J. 2010. PMID: 20621714

7

Protein kinase C regulates ezrin-radixin-moesin phosphorylation in canine osteosarcoma cells.

Hong SH, Osborne T, Ren L, Briggs J, Mazcko C, Burkett SS, Khanna C. Hong SH, et al. Vet Comp Oncol. 2011 Sep;9(3):207-18. doi: 10.1111/j.1476-5829.2010.00249.x. Epub 2010 Dec 14. Vet Comp Oncol. 2011. PMID: 21848623 Free PMC article.

8

Met interacts with EGFR and Ron in canine osteosarcoma.

McCleese JK, Bear MD, Kulp SK, Mazcko C, Khanna C, London CA. McCleese JK, et al. Vet Comp Oncol. 2013 Jun;11(2):124-39. doi: 10.1111/j.1476-5829.2011.00309.x. Epub 2011 Dec 8. Vet Comp Oncol. 2013. PMID: 22235915 Free PMC article.

9

Prospective molecular profiling of canine cancers provides a clinically relevant comparative model for evaluating personalized medicine (PMed) trials.

Paoloni M, Webb C, Mazcko C, Cherba D, Hendricks W, Lana S, Ehrhart EJ, Charles B, Fehling H, Kumar L, Vail D, Henson M, Childress M, Kitchell B, Kingsley C, Kim S, Neff M, Davis B, Khanna C, Trent J. Paoloni M, et al. PLoS One. 2014 Mar 17;9(3):e90028. doi: 10.1371/journal.pone.0090028. eCollection 2014. PLoS One. 2014. PMID: 24637659 Free PMC article.

10

Defining the Pharmacodynamic Profile and Therapeutic Index of NHS-IL12 Immunocytokine in Dogs with Malignant Melanoma.

Paoloni M, Mazcko C, Selting K, Lana S, Barber L, Phillips J, Skorupski K, Vail D, Wilson H, Biller B, Avery A, Kiupel M, LeBlanc A, Bernhardt A, Brunkhorst B, Tighe R, Khanna C. Paoloni M, et al. PLoS One. 2015 Jun 19;10(6):e0129954. doi: 10.1371/journal.pone.0129954. eCollection 2015. PLoS One. 2015. PMID: 26091536 Free PMC article.

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