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Six Decades of Research on Human Fetal Gonadal Steroids.
Connan-Perrot S, Léger T, Lelandais P, Desdoits-Lethimonier C, David A, Fowler PA, Mazaud-Guittot S. Connan-Perrot S, et al. Int J Mol Sci. 2021 Jun 22;22(13):6681. doi: 10.3390/ijms22136681. Int J Mol Sci. 2021. PMID: 34206462 Free PMC article. Review.
Paracetamol, aspirin, and indomethacin induce endocrine disturbances in the human fetal testis capable of interfering with testicular descent.
Mazaud-Guittot S, Nicolas Nicolaz C, Desdoits-Lethimonier C, Coiffec I, Ben Maamar M, Balaguer P, Kristensen DM, Chevrier C, Lavoué V, Poulain P, Dejucq-Rainsford N, Jégou B. Mazaud-Guittot S, et al. J Clin Endocrinol Metab. 2013 Nov;98(11):E1757-67. doi: 10.1210/jc.2013-2531. Epub 2013 Sep 12. J Clin Endocrinol Metab. 2013. PMID: 24030937
Loss of function mutation in the palmitoyl-transferase HHAT leads to syndromic 46,XY disorder of sex development by impeding Hedgehog protein palmitoylation and signaling.
Callier P, Calvel P, Matevossian A, Makrythanasis P, Bernard P, Kurosaka H, Vannier A, Thauvin-Robinet C, Borel C, Mazaud-Guittot S, Rolland A, Desdoits-Lethimonier C, Guipponi M, Zimmermann C, Stévant I, Kuhne F, Conne B, Santoni F, Lambert S, Huet F, Mugneret F, Jaruzelska J, Faivre L, Wilhelm D, Jégou B, Trainor PA, Resh MD, Antonarakis SE, Nef S. Callier P, et al. PLoS Genet. 2014 May 1;10(5):e1004340. doi: 10.1371/journal.pgen.1004340. eCollection 2014 May. PLoS Genet. 2014. PMID: 24784881 Free PMC article.
An investigation of the endocrine-disruptive effects of bisphenol a in human and rat fetal testes.
Ben Maamar M, Lesné L, Desdoits-Lethimonier C, Coiffec I, Lassurguère J, Lavoué V, Deceuninck Y, Antignac JP, Le Bizec B, Perdu E, Zalko D, Pineau C, Chevrier C, Dejucq-Rainsford N, Mazaud-Guittot S, Jégou B. Ben Maamar M, et al. PLoS One. 2015 Feb 23;10(2):e0117226. doi: 10.1371/journal.pone.0117226. eCollection 2015. PLoS One. 2015. PMID: 25706302 Free PMC article.
Ibuprofen results in alterations of human fetal testis development.
Ben Maamar M, Lesné L, Hennig K, Desdoits-Lethimonier C, Kilcoyne KR, Coiffec I, Rolland AD, Chevrier C, Kristensen DM, Lavoué V, Antignac JP, Le Bizec B, Dejucq-Rainsford N, Mitchell RT, Mazaud-Guittot S, Jégou B. Ben Maamar M, et al. Sci Rep. 2017 Mar 10;7:44184. doi: 10.1038/srep44184. Sci Rep. 2017. PMID: 28281692 Free PMC article.
Ibuprofen alters human testicular physiology to produce a state of compensated hypogonadism.
Kristensen DM, Desdoits-Lethimonier C, Mackey AL, Dalgaard MD, De Masi F, Munkbøl CH, Styrishave B, Antignac JP, Le Bizec B, Platel C, Hay-Schmidt A, Jensen TK, Lesné L, Mazaud-Guittot S, Kristiansen K, Brunak S, Kjaer M, Juul A, Jégou B. Kristensen DM, et al. Proc Natl Acad Sci U S A. 2018 Jan 23;115(4):E715-E724. doi: 10.1073/pnas.1715035115. Epub 2018 Jan 8. Proc Natl Acad Sci U S A. 2018. PMID: 29311296 Free PMC article. Clinical Trial.
Crosstalk between BPA and FXRα Signaling Pathways Lead to Alterations of Undifferentiated Germ Cell Homeostasis and Male Fertility Disorders.
Sèdes L, Desdoits-Lethimonier C, Rouaisnel B, Holota H, Thirouard L, Lesne L, Damon-Soubeyrand C, Martinot E, Saru JP, Mazaud-Guittot S, Caira F, Beaudoin C, Jégou B, Volle DH. Sèdes L, et al. Stem Cell Reports. 2018 Oct 9;11(4):944-958. doi: 10.1016/j.stemcr.2018.08.018. Epub 2018 Sep 20. Stem Cell Reports. 2018. PMID: 30245210 Free PMC article.
Safeguarding Female Reproductive Health against Endocrine Disrupting Chemicals-The FREIA Project.
Duursen MBMV, Boberg J, Christiansen S, Connolly L, Damdimopoulou P, Filis P, Fowler PA, Gadella BM, Holte J, Jääger K, Johansson HKL, Li T, Mazaud-Guittot S, Parent AS, Salumets A, Soto AM, Svingen T, Velthut-Meikas A, Wedebye EB, Xie Y, Berg MVD. Duursen MBMV, et al. Int J Mol Sci. 2020 May 1;21(9):3215. doi: 10.3390/ijms21093215. Int J Mol Sci. 2020. PMID: 32370092 Free PMC article. Review.
44 results