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Carrier Protein Interaction with Competing Adenylation and Epimerization Domains in a Nonribosomal Peptide Synthetase Analyzed by FRET.
Angew Chem Int Ed Engl. 2024 May 13;63(20):e202317753. doi: 10.1002/anie.202317753. Epub 2024 Apr 9.
Angew Chem Int Ed Engl. 2024.
PMID: 38488324
Subdomain dynamics enable chemical chain reactions in non-ribosomal peptide synthetases.
Sun X, Alfermann J, Li H, Watkins MB, Chen YT, Morrell TE, Mayerthaler F, Wang CY, Komatsuzaki T, Chu JW, Ando N, Mootz HD, Yang H.
Sun X, et al. Among authors: mayerthaler f.
Nat Chem. 2024 Feb;16(2):259-268. doi: 10.1038/s41557-023-01361-4. Epub 2023 Dec 4.
Nat Chem. 2024.
PMID: 38049653
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FRET Monitoring of a Nonribosomal Peptide Synthetase Elongation Module Reveals Carrier Protein Shuttling between Catalytic Domains.
Rüschenbaum J, Steinchen W, Mayerthaler F, Feldberg AL, Mootz HD.
Rüschenbaum J, et al. Among authors: mayerthaler f.
Angew Chem Int Ed Engl. 2022 Nov 25;61(48):e202212994. doi: 10.1002/anie.202212994. Epub 2022 Oct 26.
Angew Chem Int Ed Engl. 2022.
PMID: 36169151
Free PMC article.
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Intermediary conformations linked to the directionality of the aminoacylation pathway of nonribosomal peptide synthetases.
Mayerthaler F, Feldberg AL, Alfermann J, Sun X, Steinchen W, Yang H, Mootz HD.
Mayerthaler F, et al.
RSC Chem Biol. 2021 Mar 4;2(3):843-854. doi: 10.1039/d0cb00220h. eCollection 2021 Jun 1.
RSC Chem Biol. 2021.
PMID: 34458813
Free PMC article.
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Context-dependent activity of A domains in the tyrocidine synthetase.
Degen A, Mayerthaler F, Mootz HD, Di Ventura B.
Degen A, et al. Among authors: mayerthaler f.
Sci Rep. 2019 Mar 26;9(1):5119. doi: 10.1038/s41598-019-41492-8.
Sci Rep. 2019.
PMID: 30914767
Free PMC article.
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Meeting Proceedings from ICBS 2018- Toward Translational Impact.
Mayerthaler F, Finley MF, Pfeifer TA, Antolin AA.
Mayerthaler F, et al.
ACS Chem Biol. 2019 Apr 19;14(4):567-578. doi: 10.1021/acschembio.9b00169. Epub 2019 Mar 12.
ACS Chem Biol. 2019.
PMID: 30860357
No abstract available.
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FRET monitoring of a nonribosomal peptide synthetase.
Alfermann J, Sun X, Mayerthaler F, Morrell TE, Dehling E, Volkmann G, Komatsuzaki T, Yang H, Mootz HD.
Alfermann J, et al. Among authors: mayerthaler f.
Nat Chem Biol. 2017 Sep;13(9):1009-1015. doi: 10.1038/nchembio.2435. Epub 2017 Jul 24.
Nat Chem Biol. 2017.
PMID: 28759017
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