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Fortuitous somatic mutations during antibody evolution endow broad neutralization against SARS-CoV-2 Omicron variants.
Wu J, Chen Z, Gao Y, Wang Z, Wang J, Chiang BY, Zhou Y, Han Y, Zhan W, Xie M, Jiang W, Zhang X, Hao A, Xia A, He J, Xue S, Mayer CT, Wu F, Wang B, Zhang L, Sun L, Wang Q. Wu J, et al. Among authors: mayer ct. Cell Rep. 2023 May 30;42(5):112503. doi: 10.1016/j.celrep.2023.112503. Epub 2023 May 3. Cell Rep. 2023. PMID: 37178120 Free PMC article.
Characterization of cross-reactive monoclonal antibodies against SARS-CoV-1 and SARS-CoV-2: Implication for rational design and development of pan-sarbecovirus vaccines and neutralizing antibodies.
Li S, Wu J, Jiang W, He H, Zhou Y, Wu W, Gao Y, Xie M, Xia A, He J, Zhang Q, Han Y, Wang N, Zhu G, Wang Q, Zhang Z, Mayer CT, Wang K, Wang X, Wang J, Chen Z, Jiang S, Sun L, Xia R, Wang Q. Li S, et al. Among authors: mayer ct. J Med Virol. 2023 Feb;95(2):e28440. doi: 10.1002/jmv.28440. J Med Virol. 2023. PMID: 36573441 Free PMC article.
Cross-reactive antibody response to Monkeypox virus surface proteins in a small proportion of individuals with and without Chinese smallpox vaccination history.
Xia A, Wang X, He J, Wu W, Jiang W, Xue S, Zhang Q, Gao Y, Han Y, Li Y, Peng X, Xie M, Mayer CT, Liu J, Hua C, Sha Y, Xu W, Huang J, Ying T, Jiang S, Xie Y, Cai Q, Lu L, Silva IT, Yuan Z, Zhang Y, Wang Q. Xia A, et al. Among authors: mayer ct. BMC Biol. 2023 Oct 2;21(1):205. doi: 10.1186/s12915-023-01699-8. BMC Biol. 2023. PMID: 37784185 Free PMC article.
Biallelic human SHARPIN loss of function induces autoinflammation and immunodeficiency.
Oda H, Manthiram K, Chavan PP, Rieser E, Veli Ö, Kaya Ö, Rauch C, Nakabo S, Kuehn HS, Swart M, Wang Y, Çelik NI, Molitor A, Ziaee V, Movahedi N, Shahrooei M, Parvaneh N, Alipour-Olyei N, Carapito R, Xu Q, Preite S, Beck DB, Chae JJ, Nehrebecky M, Ombrello AK, Hoffmann P, Romeo T, Deuitch NT, Matthíasardóttir B, Mullikin J, Komarow H, Stoddard J, Niemela J, Dobbs K, Sweeney CL, Anderton H, Lawlor KE, Yoshitomi H, Yang D, Boehm M, Davis J, Mudd P, Randazzo D, Tsai WL, Gadina M, Kaplan MJ, Toguchida J, Mayer CT, Rosenzweig SD, Notarangelo LD, Iwai K, Silke J, Schwartzberg PL, Boisson B, Casanova JL, Bahram S, Rao AP, Peltzer N, Walczak H, Lalaoui N, Aksentijevich I, Kastner DL. Oda H, et al. Among authors: mayer ct. Nat Immunol. 2024 May;25(5):764-777. doi: 10.1038/s41590-024-01817-w. Epub 2024 Apr 12. Nat Immunol. 2024. PMID: 38609546
Fortuitous Somatic Mutations during Antibody Evolution Endow Broad Neutralization against SARS-CoV-2 Omicron Variants.
Wu J, Chen Z, Gao Y, Wang Z, Wang J, Chiang BY, Zhou Y, Han Y, Zhan W, Xie M, Jiang W, Zhang X, Hao A, Xia A, He J, Xue S, Mayer CT, Wu F, Wang B, Zhang L, Sun L, Wang Q. Wu J, et al. Among authors: mayer ct. bioRxiv [Preprint]. 2022 Dec 13:2022.12.12.520172. doi: 10.1101/2022.12.12.520172. bioRxiv. 2022. PMID: 36561175 Free PMC article. Updated. Preprint.
Guidelines for mouse and human DC generation.
Lutz MB, Ali S, Audiger C, Autenrieth SE, Berod L, Bigley V, Cyran L, Dalod M, Dörrie J, Dudziak D, Flórez-Grau G, Giusiano L, Godoy GJ, Heuer M, Krug AB, Lehmann CHK, Mayer CT, Naik SH, Scheu S, Schreibelt G, Segura E, Seré K, Sparwasser T, Tel J, Xu H, Zenke M. Lutz MB, et al. Among authors: mayer ct. Eur J Immunol. 2023 Nov;53(11):e2249816. doi: 10.1002/eji.202249816. Epub 2022 Oct 27. Eur J Immunol. 2023. PMID: 36303448 Free PMC article.
An ultrapotent pan-β-coronavirus lineage B (β-CoV-B) neutralizing antibody locks the receptor-binding domain in closed conformation by targeting its conserved epitope.
Liu Z, Xu W, Chen Z, Fu W, Zhan W, Gao Y, Zhou J, Zhou Y, Wu J, Wang Q, Zhang X, Hao A, Wu W, Zhang Q, Li Y, Fan K, Chen R, Jiang Q, Mayer CT, Schoofs T, Xie Y, Jiang S, Wen Y, Yuan Z, Wang K, Lu L, Sun L, Wang Q. Liu Z, et al. Among authors: mayer ct. Protein Cell. 2022 Sep;13(9):655-675. doi: 10.1007/s13238-021-00871-6. Epub 2021 Sep 23. Protein Cell. 2022. PMID: 34554412 Free PMC article.
47 results