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Page 1
Topography of transcriptionally active chromatin in glioblastoma.
Xu L, Chen Y, Huang Y, Sandanaraj E, Yu JS, Lin RY, Dakle P, Ke XY, Chong YK, Koh L, Mayakonda A, Nacro K, Hill J, Huang ML, Gery S, Lim SW, Huang Z, Xu Y, Chen J, Bai L, Wang S, Wakimoto H, Yeo TT, Ang BT, Müschen M, Tang C, Tan TZ, Koeffler HP. Xu L, et al. Among authors: mayakonda a. Sci Adv. 2021 Apr 30;7(18):eabd4676. doi: 10.1126/sciadv.abd4676. Print 2021 Apr. Sci Adv. 2021. PMID: 33931443 Free PMC article.
Targetable BET proteins- and E2F1-dependent transcriptional program maintains the malignancy of glioblastoma.
Xu L, Chen Y, Mayakonda A, Koh L, Chong YK, Buckley DL, Sandanaraj E, Lim SW, Lin RY, Ke XY, Huang ML, Chen J, Sun W, Wang LZ, Goh BC, Dinh HQ, Kappei D, Winter GE, Ding LW, Ang BT, Berman BP, Bradner JE, Tang C, Koeffler HP. Xu L, et al. Among authors: mayakonda a. Proc Natl Acad Sci U S A. 2018 May 29;115(22):E5086-E5095. doi: 10.1073/pnas.1712363115. Epub 2018 May 15. Proc Natl Acad Sci U S A. 2018. PMID: 29764999 Free PMC article.
Bromodomain and extraterminal proteins foster the core transcriptional regulatory programs and confer vulnerability in liposarcoma.
Chen Y, Xu L, Mayakonda A, Huang ML, Kanojia D, Tan TZ, Dakle P, Lin RY, Ke XY, Said JW, Chen J, Gery S, Ding LW, Jiang YY, Pang A, Puhaindran ME, Goh BC, Koeffler HP. Chen Y, et al. Among authors: mayakonda a. Nat Commun. 2019 Mar 22;10(1):1353. doi: 10.1038/s41467-019-09257-z. Nat Commun. 2019. PMID: 30903020 Free PMC article.
TP63, SOX2, and KLF5 Establish a Core Regulatory Circuitry That Controls Epigenetic and Transcription Patterns in Esophageal Squamous Cell Carcinoma Cell Lines.
Jiang YY, Jiang Y, Li CQ, Zhang Y, Dakle P, Kaur H, Deng JW, Lin RY, Han L, Xie JJ, Yan Y, Doan N, Zheng Y, Mayakonda A, Hazawa M, Xu L, Li Y, Aswad L, Jeitany M, Kanojia D, Guan XY, Said JW, Yang W, Fullwood MJ, Lin DC, Koeffler HP. Jiang YY, et al. Among authors: mayakonda a. Gastroenterology. 2020 Oct;159(4):1311-1327.e19. doi: 10.1053/j.gastro.2020.06.050. Epub 2020 Jun 30. Gastroenterology. 2020. PMID: 32619460
BCL6 promotes glioma and serves as a therapeutic target.
Xu L, Chen Y, Dutra-Clarke M, Mayakonda A, Hazawa M, Savinoff SE, Doan N, Said JW, Yong WH, Watkins A, Yang H, Ding LW, Jiang YY, Tyner JW, Ching J, Kovalik JP, Madan V, Chan SL, Müschen M, Breunig JJ, Lin DC, Koeffler HP. Xu L, et al. Among authors: mayakonda a. Proc Natl Acad Sci U S A. 2017 Apr 11;114(15):3981-3986. doi: 10.1073/pnas.1609758114. Epub 2017 Mar 29. Proc Natl Acad Sci U S A. 2017. PMID: 28356518 Free PMC article.
Super-Enhancers Promote Transcriptional Dysregulation in Nasopharyngeal Carcinoma.
Yuan J, Jiang YY, Mayakonda A, Huang M, Ding LW, Lin H, Yu F, Lu Y, Loh TKS, Chow M, Savage S, Tyner JW, Lin DC, Koeffler HP. Yuan J, et al. Among authors: mayakonda a. Cancer Res. 2017 Dec 1;77(23):6614-6626. doi: 10.1158/0008-5472.CAN-17-1143. Epub 2017 Sep 26. Cancer Res. 2017. PMID: 28951465 Free PMC article.
Super-enhancer-associated MEIS1 promotes transcriptional dysregulation in Ewing sarcoma in co-operation with EWS-FLI1.
Lin L, Huang M, Shi X, Mayakonda A, Hu K, Jiang YY, Guo X, Chen L, Pang B, Doan N, Said JW, Xie J, Gery S, Cheng X, Lin Z, Li J, Berman BP, Yin D, Lin DC, Koeffler HP. Lin L, et al. Among authors: mayakonda a. Nucleic Acids Res. 2019 Feb 20;47(3):1255-1267. doi: 10.1093/nar/gky1207. Nucleic Acids Res. 2019. PMID: 30496486 Free PMC article.
Targeting super-enhancer-associated oncogenes in oesophageal squamous cell carcinoma.
Jiang YY, Lin DC, Mayakonda A, Hazawa M, Ding LW, Chien WW, Xu L, Chen Y, Xiao JF, Senapedis W, Baloglu E, Kanojia D, Shang L, Xu X, Yang H, Tyner JW, Wang MR, Koeffler HP. Jiang YY, et al. Among authors: mayakonda a. Gut. 2017 Aug;66(8):1358-1368. doi: 10.1136/gutjnl-2016-311818. Epub 2016 May 10. Gut. 2017. PMID: 27196599 Free PMC article.
CARD10, a CEBPE target involved in granulocytic differentiation.
Shyamsunder P, Sankar H, Mayakonda A, Han L, Nordin HBM, Woon TW, Shanmugasundaram M, Dakle P, Madan V, Koeffler HP. Shyamsunder P, et al. Among authors: mayakonda a. Haematologica. 2018 Aug;103(8):1269-1277. doi: 10.3324/haematol.2018.190280. Epub 2018 May 17. Haematologica. 2018. PMID: 29773596 Free PMC article.
ARID1A and CEBPα cooperatively inhibit UCA1 transcription in breast cancer.
Guo X, Zhang Y, Mayakonda A, Madan V, Ding LW, Lin LH, Zia S, Gery S, Tyner JW, Zhou W, Yin D, Lin DC, Koeffler HP. Guo X, et al. Among authors: mayakonda a. Oncogene. 2018 Nov;37(45):5939-5951. doi: 10.1038/s41388-018-0371-4. Epub 2018 Jul 6. Oncogene. 2018. PMID: 29980791
50 results