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Disrupted CaV1.2 selectivity causes overlapping long QT and Brugada syndrome phenotypes in the CACNA1C-E1115K iPS cell model.
Heart Rhythm. 2023 Jan;20(1):89-99. doi: 10.1016/j.hrthm.2022.08.021. Epub 2022 Aug 23.
Heart Rhythm. 2023.
PMID: 36007726
Synergistic gene editing in human iPS cells via cell cycle and DNA repair modulation.
Maurissen TL, Woltjen K.
Maurissen TL, et al.
Nat Commun. 2020 Jun 8;11(1):2876. doi: 10.1038/s41467-020-16643-5.
Nat Commun. 2020.
PMID: 32513994
Free PMC article.
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Recapitulating the human segmentation clock with pluripotent stem cells.
Matsuda M, Yamanaka Y, Uemura M, Osawa M, Saito MK, Nagahashi A, Nishio M, Guo L, Ikegawa S, Sakurai S, Kihara S, Maurissen TL, Nakamura M, Matsumoto T, Yoshitomi H, Ikeya M, Kawakami N, Yamamoto T, Woltjen K, Ebisuya M, Toguchida J, Alev C.
Matsuda M, et al. Among authors: maurissen tl.
Nature. 2020 Apr;580(7801):124-129. doi: 10.1038/s41586-020-2144-9. Epub 2020 Apr 1.
Nature. 2020.
PMID: 32238941
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Modeling early pathophysiological phenotypes of diabetic retinopathy in a human inner blood-retinal barrier-on-a-chip.
Maurissen TL, Spielmann AJ, Schellenberg G, Bickle M, Vieira JR, Lai SY, Pavlou G, Fauser S, Westenskow PD, Kamm RD, Ragelle H.
Maurissen TL, et al.
Nat Commun. 2024 Feb 14;15(1):1372. doi: 10.1038/s41467-024-45456-z.
Nat Commun. 2024.
PMID: 38355716
Free PMC article.
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Modeling mutation-specific arrhythmogenic phenotypes in isogenic human iPSC-derived cardiac tissues.
Maurissen TL, Kawatou M, López-Dávila V, Minatoya K, Yamashita JK, Woltjen K.
Maurissen TL, et al.
Sci Rep. 2024 Jan 31;14(1):2586. doi: 10.1038/s41598-024-52871-1.
Sci Rep. 2024.
PMID: 38297132
Free PMC article.
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ACE2 knockout hinders SARS-CoV-2 propagation in iPS cell-derived airway and alveolar epithelial cells.
Niwa R, Sakai K, Lung MSY, Matsumoto T, Mikawa R, Maehana S, Suzuki M, Yamamoto Y, Maurissen TL, Hirabayashi A, Noda T, Kubo M, Gotoh S, Woltjen K.
Niwa R, et al. Among authors: maurissen tl.
Front Cell Dev Biol. 2023 Dec 8;11:1290876. doi: 10.3389/fcell.2023.1290876. eCollection 2023.
Front Cell Dev Biol. 2023.
PMID: 38149046
Free PMC article.
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Novel Calmodulin Variant p.E46K Associated With Severe Catecholaminergic Polymorphic Ventricular Tachycardia Produces Robust Arrhythmogenicity in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.
Gao J, Makiyama T, Yamamoto Y, Kobayashi T, Aoki H, Maurissen TL, Wuriyanghai Y, Kashiwa A, Imamura T, Aizawa T, Huang H, Kohjitani H, Nishikawa M, Chonabayashi K, Fukuyama M, Manabe H, Nakau K, Wada T, Kato K, Toyoda F, Yoshida Y, Makita N, Woltjen K, Ohno S, Kurebayashi N, Murayama T, Sakurai T, Horie M, Kimura T.
Gao J, et al. Among authors: maurissen tl.
Circ Arrhythm Electrophysiol. 2023 Mar;16(3):e011387. doi: 10.1161/CIRCEP.122.011387. Epub 2023 Mar 3.
Circ Arrhythm Electrophysiol. 2023.
PMID: 36866681
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Microphysiological Neurovascular Barriers to Model the Inner Retinal Microvasculature.
Maurissen TL, Pavlou G, Bichsel C, Villaseñor R, Kamm RD, Ragelle H.
Maurissen TL, et al.
J Pers Med. 2022 Jan 24;12(2):148. doi: 10.3390/jpm12020148.
J Pers Med. 2022.
PMID: 35207637
Free PMC article.
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