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NAD+ Replenishment Improves Lifespan and Healthspan in Ataxia Telangiectasia Models via Mitophagy and DNA Repair.
Fang EF, Kassahun H, Croteau DL, Scheibye-Knudsen M, Marosi K, Lu H, Shamanna RA, Kalyanasundaram S, Bollineni RC, Wilson MA, Iser WB, Wollman BN, Morevati M, Li J, Kerr JS, Lu Q, Waltz TB, Tian J, Sinclair DA, Mattson MP, Nilsen H, Bohr VA. Fang EF, et al. Among authors: mattson mp. Cell Metab. 2016 Oct 11;24(4):566-581. doi: 10.1016/j.cmet.2016.09.004. Cell Metab. 2016. PMID: 27732836 Free PMC article.
A high-fat diet and NAD(+) activate Sirt1 to rescue premature aging in cockayne syndrome.
Scheibye-Knudsen M, Mitchell SJ, Fang EF, Iyama T, Ward T, Wang J, Dunn CA, Singh N, Veith S, Hasan-Olive MM, Mangerich A, Wilson MA, Mattson MP, Bergersen LH, Cogger VC, Warren A, Le Couteur DG, Moaddel R, Wilson DM 3rd, Croteau DL, de Cabo R, Bohr VA. Scheibye-Knudsen M, et al. Among authors: mattson mp. Cell Metab. 2014 Nov 4;20(5):840-855. doi: 10.1016/j.cmet.2014.10.005. Epub 2014 Nov 4. Cell Metab. 2014. PMID: 25440059 Free PMC article.
Loss of NEIL1 causes defects in olfactory function in mice.
Canugovi C, Misiak M, Scheibye-Knudsen M, Croteau DL, Mattson MP, Bohr VA. Canugovi C, et al. Among authors: mattson mp. Neurobiol Aging. 2015 Feb;36(2):1007-12. doi: 10.1016/j.neurobiolaging.2014.09.026. Epub 2014 Oct 14. Neurobiol Aging. 2015. PMID: 25448603 Free PMC article.
Nuclear DNA damage signalling to mitochondria in ageing.
Fang EF, Scheibye-Knudsen M, Chua KF, Mattson MP, Croteau DL, Bohr VA. Fang EF, et al. Among authors: mattson mp. Nat Rev Mol Cell Biol. 2016 May;17(5):308-21. doi: 10.1038/nrm.2016.14. Epub 2016 Mar 9. Nat Rev Mol Cell Biol. 2016. PMID: 26956196 Free PMC article. Review.
Mitophagy and Alzheimer's Disease: Cellular and Molecular Mechanisms.
Kerr JS, Adriaanse BA, Greig NH, Mattson MP, Cader MZ, Bohr VA, Fang EF. Kerr JS, et al. Among authors: mattson mp. Trends Neurosci. 2017 Mar;40(3):151-166. doi: 10.1016/j.tins.2017.01.002. Epub 2017 Feb 9. Trends Neurosci. 2017. PMID: 28190529 Free PMC article. Review.
980 results