Matthews ML - Search Results

1

Enterococci enhance Clostridioides difficile pathogenesis.

Smith AB, Jenior ML, Keenan O, Hart JL, Specker J, Abbas A, Rangel PC, Di C, Green J, Bustin KA, Gaddy JA, Nicholson MR, Laut C, Kelly BJ, Matthews ML, Evans DR, Van Tyne D, Furth EE, Papin JA, Bushman FD, Erlichman J, Baldassano RN, Silverman MA, Dunny GM, Prentice BM, Skaar EP, Zackular JP. Smith AB, et al. Among authors: matthews ml. Nature. 2022 Nov;611(7937):780-786. doi: 10.1038/s41586-022-05438-x. Epub 2022 Nov 16. Nature. 2022. PMID: 36385534 Free PMC article.

2

Discovery of Potent and Selective Inhibitors against Protein-Derived Electrophilic Cofactors.

Wang X, Lin Z, Bustin KA, McKnight NR, Parsons WH, Matthews ML. Wang X, et al. Among authors: matthews ml. J Am Chem Soc. 2022 Mar 30;144(12):5377-5388. doi: 10.1021/jacs.1c12748. Epub 2022 Mar 2. J Am Chem Soc. 2022. PMID: 35235319 Free PMC article.

3

Characterizing metabolic drivers of Clostridioides difficile infection with activity-based hydrazine probes.

Bustin KA, Abbas A, Wang X, Abt MC, Zackular JP, Matthews ML. Bustin KA, et al. Among authors: matthews ml. Front Pharmacol. 2023 Jan 26;14:1074619. doi: 10.3389/fphar.2023.1074619. eCollection 2023. Front Pharmacol. 2023. PMID: 36778002 Free PMC article.

4

Activity-Based Hydrazine Probes for Protein Profiling of Electrophilic Functionality in Therapeutic Targets.

Lin Z, Wang X, Bustin KA, Shishikura K, McKnight NR, He L, Suciu RM, Hu K, Han X, Ahmadi M, Olson EJ, Parsons WH, Matthews ML. Lin Z, et al. Among authors: matthews ml. ACS Cent Sci. 2021 Sep 22;7(9):1524-1534. doi: 10.1021/acscentsci.1c00616. Epub 2021 Aug 19. ACS Cent Sci. 2021. PMID: 34584954 Free PMC article.

5

Elucidation of the Fe(IV)=O intermediate in the catalytic cycle of the halogenase SyrB2.

Wong SD, Srnec M, Matthews ML, Liu LV, Kwak Y, Park K, Bell CB 3rd, Alp EE, Zhao J, Yoda Y, Kitao S, Seto M, Krebs C, Bollinger JM Jr, Solomon EI. Wong SD, et al. Among authors: matthews ml. Nature. 2013 Jul 18;499(7458):320-3. doi: 10.1038/nature12304. Nature. 2013. PMID: 23868262 Free PMC article.

6

Direct nitration and azidation of aliphatic carbons by an iron-dependent halogenase.

Matthews ML, Chang WC, Layne AP, Miles LA, Krebs C, Bollinger JM Jr. Matthews ML, et al. Nat Chem Biol. 2014 Mar;10(3):209-15. doi: 10.1038/nchembio.1438. Epub 2014 Jan 26. Nat Chem Biol. 2014. PMID: 24463698 Free PMC article.

7

Design of activated serine-containing catalytic triads with atomic-level accuracy.

Rajagopalan S, Wang C, Yu K, Kuzin AP, Richter F, Lew S, Miklos AE, Matthews ML, Seetharaman J, Su M, Hunt JF, Cravatt BF, Baker D. Rajagopalan S, et al. Among authors: matthews ml. Nat Chem Biol. 2014 May;10(5):386-91. doi: 10.1038/nchembio.1498. Epub 2014 Apr 6. Nat Chem Biol. 2014. PMID: 24705591 Free PMC article.

8

Chemoproteomic profiling and discovery of protein electrophiles in human cells.

Matthews ML, He L, Horning BD, Olson EJ, Correia BE, Yates JR 3rd, Dawson PE, Cravatt BF. Matthews ML, et al. Nat Chem. 2017 Mar;9(3):234-243. doi: 10.1038/nchem.2645. Epub 2016 Oct 31. Nat Chem. 2017. PMID: 28221344 Free PMC article.

9

Substrate positioning controls the partition between halogenation and hydroxylation in the aliphatic halogenase, SyrB2.

Matthews ML, Neumann CS, Miles LA, Grove TL, Booker SJ, Krebs C, Walsh CT, Bollinger JM Jr. Matthews ML, et al. Proc Natl Acad Sci U S A. 2009 Oct 20;106(42):17723-8. doi: 10.1073/pnas.0909649106. Epub 2009 Oct 6. Proc Natl Acad Sci U S A. 2009. PMID: 19815524 Free PMC article.

10

Biochemistry. Remote enzyme microsurgery.

Bollinger JM Jr, Matthews ML. Bollinger JM Jr, et al. Among authors: matthews ml. Science. 2010 Mar 12;327(5971):1337-8. doi: 10.1126/science.1187421. Science. 2010. PMID: 20223975 No abstract available.

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