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Bioactive Thymosin Alpha-1 Does Not Influence F508del-CFTR Maturation and Activity.
Armirotti A, Tomati V, Matthes E, Veit G, Cholon DM, Phuan PW, Braccia C, Guidone D, Gentzsch M, Lukacs GL, Verkman AS, Galietta LJV, Hanrahan JW, Pedemonte N. Armirotti A, et al. Among authors: matthes e. Sci Rep. 2019 Jul 16;9(1):10310. doi: 10.1038/s41598-019-46639-1. Sci Rep. 2019. PMID: 31311979 Free PMC article.
Corrector combination therapies for F508del-CFTR.
Hanrahan JW, Matthes E, Carlile G, Thomas DY. Hanrahan JW, et al. Among authors: matthes e. Curr Opin Pharmacol. 2017 Jun;34:105-111. doi: 10.1016/j.coph.2017.09.016. Epub 2017 Nov 5. Curr Opin Pharmacol. 2017. PMID: 29080476 Review.
F508del-CFTR is not corrected by thymosin α1.
Matthes E, Hanrahan JW, Cantin AM. Matthes E, et al. Nat Med. 2018 Jul;24(7):890-891. doi: 10.1038/s41591-018-0079-6. Nat Med. 2018. PMID: 29942095 No abstract available.
The dual phosphodiesterase 3 and 4 inhibitor RPL554 stimulates CFTR and ciliary beating in primary cultures of bronchial epithelia.
Turner MJ, Matthes E, Billet A, Ferguson AJ, Thomas DY, Randell SH, Ostrowski LE, Abbott-Banner K, Hanrahan JW. Turner MJ, et al. Among authors: matthes e. Am J Physiol Lung Cell Mol Physiol. 2016 Jan 1;310(1):L59-70. doi: 10.1152/ajplung.00324.2015. Epub 2015 Nov 6. Am J Physiol Lung Cell Mol Physiol. 2016. PMID: 26545902 Free article.
Latonduine Analogs Restore F508del-Cystic Fibrosis Transmembrane Conductance Regulator Trafficking through the Modulation of Poly-ADP Ribose Polymerase 3 and Poly-ADP Ribose Polymerase 16 Activity.
Carlile GW, Robert R, Matthes E, Yang Q, Solari R, Hatley R, Edge CM, Hanrahan JW, Andersen R, Thomas DY, Birault V. Carlile GW, et al. Among authors: matthes e. Mol Pharmacol. 2016 Aug;90(2):65-79. doi: 10.1124/mol.115.102418. Epub 2016 May 18. Mol Pharmacol. 2016. PMID: 27193581
67 results