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Prostaglandin E2 receptor PTGER4-expressing macrophages promote intestinal epithelial barrier regeneration upon inflammation.
Na YR, Jung D, Stakenborg M, Jang H, Gu GJ, Jeong MR, Suh SY, Kim HJ, Kwon YH, Sung TS, Ryoo SB, Park KJ, Im JP, Park JY, Lee YS, Han H, Park B, Lee S, Kim D, Lee HS, Cleynen I, Matteoli G, Seok SH. Na YR, et al. Among authors: matteoli g. Gut. 2021 Dec;70(12):2249-2260. doi: 10.1136/gutjnl-2020-322146. Epub 2021 Feb 7. Gut. 2021. PMID: 33558271
The intestinal cholinergic anti-inflammatory pathway.
Goverse G, Stakenborg M, Matteoli G. Goverse G, et al. Among authors: matteoli g. J Physiol. 2016 Oct 15;594(20):5771-5780. doi: 10.1113/JP271537. Epub 2016 May 5. J Physiol. 2016. PMID: 26959627 Free PMC article. Review.
CCR2-dependent monocyte-derived macrophages resolve inflammation and restore gut motility in postoperative ileus.
Farro G, Stakenborg M, Gomez-Pinilla PJ, Labeeuw E, Goverse G, Di Giovangiulio M, Stakenborg N, Meroni E, D'Errico F, Elkrim Y, Laoui D, Lisowski ZM, Sauter KA, Hume DA, Van Ginderachter JA, Boeckxstaens GE, Matteoli G. Farro G, et al. Among authors: matteoli g. Gut. 2017 Dec;66(12):2098-2109. doi: 10.1136/gutjnl-2016-313144. Epub 2017 Jun 14. Gut. 2017. PMID: 28615302 Free article.
Estrogen receptor β controls proliferation of enteric glia and differentiation of neurons in the myenteric plexus after damage.
D'Errico F, Goverse G, Dai Y, Wu W, Stakenborg M, Labeeuw E, De Simone V, Verstockt B, Gomez-Pinilla PJ, Warner M, Di Leo A, Matteoli G, Gustafsson JA. D'Errico F, et al. Among authors: matteoli g. Proc Natl Acad Sci U S A. 2018 May 29;115(22):5798-5803. doi: 10.1073/pnas.1720267115. Epub 2018 May 14. Proc Natl Acad Sci U S A. 2018. PMID: 29760072 Free PMC article.
Preoperative administration of the 5-HT4 receptor agonist prucalopride reduces intestinal inflammation and shortens postoperative ileus via cholinergic enteric neurons.
Stakenborg N, Labeeuw E, Gomez-Pinilla PJ, De Schepper S, Aerts R, Goverse G, Farro G, Appeltans I, Meroni E, Stakenborg M, Viola MF, Gonzalez-Dominguez E, Bosmans G, Alpizar YA, Wolthuis A, D'Hoore A, Van Beek K, Verheijden S, Verhaegen M, Derua R, Waelkens E, Moretti M, Gotti C, Augustijns P, Talavera K, Vanden Berghe P, Matteoli G, Boeckxstaens GE. Stakenborg N, et al. Among authors: matteoli g. Gut. 2019 Aug;68(8):1406-1416. doi: 10.1136/gutjnl-2018-317263. Epub 2018 Nov 24. Gut. 2019. PMID: 30472681 Free PMC article. Clinical Trial.
84 results