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Loss of CtBP2 may be a mechanistic link between metabolic derangements and progressive impairment of pancreatic β cell function.
Sekiya M, Ma Y, Kainoh K, Saito K, Yamazaki D, Tsuyuzaki T, Chen W, Adi Putri PIP, Ohno H, Miyamoto T, Takeuchi Y, Murayama Y, Sugano Y, Osaki Y, Iwasaki H, Yahagi N, Suzuki H, Motomura K, Matsuzaka T, Murata K, Mizuno S, Takahashi S, Shimano H. Sekiya M, et al. Among authors: matsuzaka t. Cell Rep. 2023 Aug 29;42(8):112914. doi: 10.1016/j.celrep.2023.112914. Epub 2023 Aug 8. Cell Rep. 2023. PMID: 37557182 Free article.
Absence of sterol regulatory element-binding protein-1 (SREBP-1) ameliorates fatty livers but not obesity or insulin resistance in Lep(ob)/Lep(ob) mice.
Yahagi N, Shimano H, Hasty AH, Matsuzaka T, Ide T, Yoshikawa T, Amemiya-Kudo M, Tomita S, Okazaki H, Tamura Y, Iizuka Y, Ohashi K, Osuga J, Harada K, Gotoda T, Nagai R, Ishibashi S, Yamada N. Yahagi N, et al. Among authors: matsuzaka t. J Biol Chem. 2002 May 31;277(22):19353-7. doi: 10.1074/jbc.M201584200. Epub 2002 Mar 28. J Biol Chem. 2002. PMID: 11923308 Free article.
Cross-talk between peroxisome proliferator-activated receptor (PPAR) alpha and liver X receptor (LXR) in nutritional regulation of fatty acid metabolism. I. PPARs suppress sterol regulatory element binding protein-1c promoter through inhibition of LXR signaling.
Yoshikawa T, Ide T, Shimano H, Yahagi N, Amemiya-Kudo M, Matsuzaka T, Yatoh S, Kitamine T, Okazaki H, Tamura Y, Sekiya M, Takahashi A, Hasty AH, Sato R, Sone H, Osuga J, Ishibashi S, Yamada N. Yoshikawa T, et al. Among authors: matsuzaka t. Mol Endocrinol. 2003 Jul;17(7):1240-54. doi: 10.1210/me.2002-0190. Epub 2003 May 1. Mol Endocrinol. 2003. PMID: 12730331
Cross-talk between peroxisome proliferator-activated receptor (PPAR) alpha and liver X receptor (LXR) in nutritional regulation of fatty acid metabolism. II. LXRs suppress lipid degradation gene promoters through inhibition of PPAR signaling.
Ide T, Shimano H, Yoshikawa T, Yahagi N, Amemiya-Kudo M, Matsuzaka T, Nakakuki M, Yatoh S, Iizuka Y, Tomita S, Ohashi K, Takahashi A, Sone H, Gotoda T, Osuga J, Ishibashi S, Yamada N. Ide T, et al. Among authors: matsuzaka t. Mol Endocrinol. 2003 Jul;17(7):1255-67. doi: 10.1210/me.2002-0191. Epub 2003 May 1. Mol Endocrinol. 2003. PMID: 12730332
Taken together with data from the accompanying paper (Yoshikawa, T., T. Ide, H. Shimano, N. Yahagi, M. Amemiya-Kudo, T. Matsuzaka, S. Yatoh, T. Kitamine, H. Okazaki, Y. Tamura, M. Sekiya, A. Takahashi, A. ...
Taken together with data from the accompanying paper (Yoshikawa, T., T. Ide, H. Shimano, N. Yahagi, M. Amemiya-Kudo, T. …
p53 Activation in adipocytes of obese mice.
Yahagi N, Shimano H, Matsuzaka T, Najima Y, Sekiya M, Nakagawa Y, Ide T, Tomita S, Okazaki H, Tamura Y, Iizuka Y, Ohashi K, Gotoda T, Nagai R, Kimura S, Ishibashi S, Osuga J, Yamada N. Yahagi N, et al. Among authors: matsuzaka t. J Biol Chem. 2003 Jul 11;278(28):25395-400. doi: 10.1074/jbc.M302364200. Epub 2003 May 6. J Biol Chem. 2003. PMID: 12734185 Free article.
SREBP-1 interacts with hepatocyte nuclear factor-4 alpha and interferes with PGC-1 recruitment to suppress hepatic gluconeogenic genes.
Yamamoto T, Shimano H, Nakagawa Y, Ide T, Yahagi N, Matsuzaka T, Nakakuki M, Takahashi A, Suzuki H, Sone H, Toyoshima H, Sato R, Yamada N. Yamamoto T, et al. Among authors: matsuzaka t. J Biol Chem. 2004 Mar 26;279(13):12027-35. doi: 10.1074/jbc.M310333200. Epub 2004 Jan 13. J Biol Chem. 2004. PMID: 14722127 Free article.
p53 involvement in the pathogenesis of fatty liver disease.
Yahagi N, Shimano H, Matsuzaka T, Sekiya M, Najima Y, Okazaki S, Okazaki H, Tamura Y, Iizuka Y, Inoue N, Nakagawa Y, Takeuchi Y, Ohashi K, Harada K, Gotoda T, Nagai R, Kadowaki T, Ishibashi S, Osuga J, Yamada N. Yahagi N, et al. Among authors: matsuzaka t. J Biol Chem. 2004 May 14;279(20):20571-5. doi: 10.1074/jbc.M400884200. Epub 2004 Feb 25. J Biol Chem. 2004. PMID: 14985341 Free article.
178 results