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Isololiolide, a carotenoid metabolite isolated from the brown alga Cystoseira tamariscifolia, is cytotoxic and able to induce apoptosis in hepatocarcinoma cells through caspase-3 activation, decreased Bcl-2 levels, increased p53 expression and PARP cleavage.
Vizetto-Duarte C, Custódio L, Gangadhar KN, Lago JH, Dias C, Matos AM, Neng N, Nogueira JM, Barreira L, Albericio F, Rauter AP, Varela J. Vizetto-Duarte C, et al. Among authors: matos am. Phytomedicine. 2016 May 15;23(5):550-7. doi: 10.1016/j.phymed.2016.02.008. Epub 2016 Feb 26. Phytomedicine. 2016. PMID: 27064014 Free article.
Exploiting the therapeutic potential of 8-β-d-glucopyranosylgenistein: synthesis, antidiabetic activity, and molecular interaction with islet amyloid polypeptide and amyloid β-peptide (1-42).
Jesus AR, Dias C, Matos AM, de Almeida RF, Viana AS, Marcelo F, Ribeiro RT, Macedo MP, Airoldi C, Nicotra F, Martins A, Cabrita EJ, Jiménez-Barbero J, Rauter AP. Jesus AR, et al. Among authors: matos am. J Med Chem. 2014 Nov 26;57(22):9463-72. doi: 10.1021/jm501069h. Epub 2014 Nov 12. J Med Chem. 2014. PMID: 25347820
Biogenic silver nanoparticle exhibits schistosomicidal activity in vitro and reduces the parasitic burden in experimental schistosomiasis mansoni.
Detoni MB, Bortoleti BTDS, Tomiotto-Pellissier F, Concato VM, Gonçalves MD, Silva TF, Ortiz LSF, Gomilde AC, Rodrigues ACJ, de Matos RLN, Bracarense APFRL, de Matos AMRN, Simão ANC, Endo TH, Kobayashi RKT, Nakazato G, Costa IN, Conchon-Costa I, Oliveira FJA, Pavanelli WR, Miranda-Sapla MM. Detoni MB, et al. Among authors: de matos amrn. Microbes Infect. 2023 Sep-Oct;25(7):105145. doi: 10.1016/j.micinf.2023.105145. Epub 2023 Apr 28. Microbes Infect. 2023. PMID: 37120010
68 results