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Identification and Biochemical Characterization of Pyrrolidinediones as Novel Inhibitors of the Bacterial Enzyme MurA.
Fathalla RK, Fröhner W, Bader CD, Fischer PD, Dahlem C, Chatterjee D, Mathea S, Kiemer AK, Arthanari H, Müller R, Abdel-Halim M, Ducho C, Engel M. Fathalla RK, et al. Among authors: mathea s. J Med Chem. 2022 Nov 10;65(21):14740-14763. doi: 10.1021/acs.jmedchem.2c01275. Epub 2022 Oct 21. J Med Chem. 2022. PMID: 36269107 Free PMC article.
Pan-SMARCA/PB1 Bromodomain Inhibitors and Their Role in Regulating Adipogenesis.
Wanior M, Preuss F, Ni X, Krämer A, Mathea S, Göbel T, Heidenreich D, Simonyi S, Kahnt AS, Joerger AC, Knapp S. Wanior M, et al. Among authors: mathea s. J Med Chem. 2020 Dec 10;63(23):14680-14699. doi: 10.1021/acs.jmedchem.0c01242. Epub 2020 Nov 20. J Med Chem. 2020. PMID: 33216538
Conformational plasticity of the ULK3 kinase domain.
Mathea S, Salah E, Tallant C, Chatterjee D, Berger BT, Konietzny R, Müller S, Kessler BM, Knapp S. Mathea S, et al. Biochem J. 2021 Jul 30;478(14):2811-2823. doi: 10.1042/BCJ20210257. Biochem J. 2021. PMID: 34190988
Development of a Selective Dual Discoidin Domain Receptor (DDR)/p38 Kinase Chemical Probe.
Röhm S, Berger BT, Schröder M, Chatterjee D, Mathea S, Joerger AC, Pinkas DM, Bufton JC, Tjaden A, Kovooru L, Kudolo M, Pohl C, Bullock AN, Müller S, Laufer S, Knapp S. Röhm S, et al. Among authors: mathea s. J Med Chem. 2021 Sep 23;64(18):13451-13474. doi: 10.1021/acs.jmedchem.1c00868. Epub 2021 Sep 10. J Med Chem. 2021. PMID: 34506142
Structural Aspects of LIMK Regulation and Pharmacology.
Chatterjee D, Preuss F, Dederer V, Knapp S, Mathea S. Chatterjee D, et al. Among authors: mathea s. Cells. 2022 Jan 2;11(1):142. doi: 10.3390/cells11010142. Cells. 2022. PMID: 35011704 Free PMC article. Review.
Enabling pseudokinases as potential drug targets.
Preuss F, Chatterjee D, Dederer V, Knapp S, Mathea S. Preuss F, et al. Among authors: mathea s. Methods Enzymol. 2022;667:663-683. doi: 10.1016/bs.mie.2022.03.050. Epub 2022 Apr 13. Methods Enzymol. 2022. PMID: 35525558
39 results