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PM534, an Optimized Target-Protein Interaction Strategy through the Colchicine Site of Tubulin.
Lucena-Agell D, Guillén MJ, Matesanz R, Álvarez-Bernad B, Hortigüela R, Avilés P, Martínez-Díez M, Santamaría-Núñez G, Contreras J, Plaza-Menacho I, Giménez-Abián JF, Oliva MA, Cuevas C, Díaz JF. Lucena-Agell D, et al. Among authors: matesanz r. J Med Chem. 2024 Feb 22;67(4):2619-2630. doi: 10.1021/acs.jmedchem.3c01775. Epub 2024 Jan 31. J Med Chem. 2024. PMID: 38294341 Free PMC article.
Modulation of taxane binding to tubulin curved and straight conformations by systematic 3'N modification provides for improved microtubule binding, persistent cytotoxicity and in vivo potency.
Ma Y, Josa-Prado F, Essif JN, Liu S, Li S, Lucena-Agell D, Chan PY, Goossens K, Hortigüela R, Matesanz R, Wang Y, Gago F, Wang H, Risinger A, Diaz JF, Fang WS. Ma Y, et al. Among authors: matesanz r. Eur J Med Chem. 2023 Nov 5;259:115668. doi: 10.1016/j.ejmech.2023.115668. Epub 2023 Jul 19. Eur J Med Chem. 2023. PMID: 37490800
Enzyme adaptation to habitat thermal legacy shapes the thermal plasticity of marine microbiomes.
Marasco R, Fusi M, Coscolín C, Barozzi A, Almendral D, Bargiela R, Nutschel CGN, Pfleger C, Dittrich J, Gohlke H, Matesanz R, Sanchez-Carrillo S, Mapelli F, Chernikova TN, Golyshin PN, Ferrer M, Daffonchio D. Marasco R, et al. Among authors: matesanz r. Nat Commun. 2023 Feb 24;14(1):1045. doi: 10.1038/s41467-023-36610-0. Nat Commun. 2023. PMID: 36828822 Free PMC article.
COVID-SCORE Spain: public perceptions of key government COVID-19 control measures.
White TM, Cash-Gibson L, Martin-Moreno JM, Matesanz R, Crespo J, Alfonso-Sanchez JL, Villapol S, El-Mohandes A, Lazarus JV. White TM, et al. Among authors: matesanz r. Eur J Public Health. 2021 Oct 26;31(5):1095-1102. doi: 10.1093/eurpub/ckab066. Eur J Public Health. 2021. PMID: 33872348 Free PMC article.
Harnessing DNA for nanothermometry.
Spicer G, Gutierrez-Erlandsson S, Matesanz R, Bernard H, Adam AP, Efeyan A, Thompson S. Spicer G, et al. Among authors: matesanz r. J Biophotonics. 2021 Feb;14(2):e202000341. doi: 10.1002/jbio.202000341. Epub 2020 Nov 19. J Biophotonics. 2021. PMID: 33128802 Free PMC article.
Direct-acting antivirals are effective and safe in HCV/HIV-coinfected liver transplant recipients who experience recurrence of hepatitis C: A prospective nationwide cohort study.
Manzardo C, Londoño MC, Castells L, Testillano M, Luis Montero J, Peñafiel J, Subirana M, Moreno A, Aguilera V, Luisa González-Diéguez M, Calvo-Pulido J, Xiol X, Salcedo M, Cuervas-Mons V, Manuel Sousa J, Suarez F, Serrano T, Ignacio Herrero J, Jiménez M, Fernandez JR, Giménez C, Del Campo S, Esteban-Mur JI, Crespo G, Moreno A, de la Rosa G, Rimola A, Miro JM; FIPSE LT-HIV investigators. Manzardo C, et al. Am J Transplant. 2018 Oct;18(10):2513-2522. doi: 10.1111/ajt.14996. Epub 2018 Aug 13. Am J Transplant. 2018. PMID: 29963780 Free article.
Analysis of the Spanish CCR5-∆32 inventory of cord blood units: lower cell counts in homozygous donors.
Enrich E, Vidal F, Sánchez-Gordo F, Gómez-Zumaquero JM, Balas A, Rudilla F, Barea L, Castro A, Larrea L, Perez-Vaquero MA, Prat I, Querol S, Garrido G, Matesanz R, Carreras E, Duarte RF. Enrich E, et al. Among authors: matesanz r. Bone Marrow Transplant. 2018 Jun;53(6):741-748. doi: 10.1038/s41409-018-0114-8. Epub 2018 Feb 6. Bone Marrow Transplant. 2018. PMID: 29410548 Free article.
Triazolopyrimidines Are Microtubule-Stabilizing Agents that Bind the Vinca Inhibitor Site of Tubulin.
Sáez-Calvo G, Sharma A, Balaguer FA, Barasoain I, Rodríguez-Salarichs J, Olieric N, Muñoz-Hernández H, Berbís MÁ, Wendeborn S, Peñalva MA, Matesanz R, Canales Á, Prota AE, Jímenez-Barbero J, Andreu JM, Lamberth C, Steinmetz MO, Díaz JF. Sáez-Calvo G, et al. Among authors: matesanz r. Cell Chem Biol. 2017 Jun 22;24(6):737-750.e6. doi: 10.1016/j.chembiol.2017.05.016. Epub 2017 Jun 1. Cell Chem Biol. 2017. PMID: 28579361 Free article.
217 results