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Altered Coordination of Individual Catalytic Steps in Different and Evolved Inteins Reveals Kinetic Plasticity of the Protein Splicing Pathway.
J Am Chem Soc. 2018 Sep 12;140(36):11267-11275. doi: 10.1021/jacs.8b04794. Epub 2018 Aug 29.
J Am Chem Soc. 2018.
PMID: 30111090
A functional interplay between intein and extein sequences in protein splicing compensates for the essential block B histidine.
Friedel K, Popp MA, Matern JCJ, Gazdag EM, Thiel IV, Volkmann G, Blankenfeldt W, Mootz HD.
Friedel K, et al. Among authors: matern jcj.
Chem Sci. 2018 Oct 3;10(1):239-251. doi: 10.1039/c8sc01074a. eCollection 2019 Jan 7.
Chem Sci. 2018.
PMID: 30713635
Free PMC article.
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Generation of a genetically encoded, photoactivatable intein for the controlled production of cyclic peptides.
Böcker JK, Friedel K, Matern JC, Bachmann AL, Mootz HD.
Böcker JK, et al.
Angew Chem Int Ed Engl. 2015 Feb 9;54(7):2116-20. doi: 10.1002/anie.201409848. Epub 2014 Dec 30.
Angew Chem Int Ed Engl. 2015.
PMID: 25557882
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Ligation of synthetic peptides to proteins using semisynthetic protein trans-splicing.
Matern JC, Bachmann AL, Thiel IV, Volkmann G, Wasmuth A, Binschik J, Mootz HD.
Matern JC, et al.
Methods Mol Biol. 2015;1266:129-43. doi: 10.1007/978-1-4939-2272-7_9.
Methods Mol Biol. 2015.
PMID: 25560072
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Chemical-tag labeling of proteins using fully recombinant split inteins.
Bachmann AL, Matern JC, Schütz V, Mootz HD.
Bachmann AL, et al.
Methods Mol Biol. 2015;1266:145-59. doi: 10.1007/978-1-4939-2272-7_10.
Methods Mol Biol. 2015.
PMID: 25560073
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Mapping of the Communication-Mediating Interface in Nonribosomal Peptide Synthetases Using a Genetically Encoded Photocrosslinker Supports an Upside-Down Helix-Hand Motif.
Dehling E, Volkmann G, Matern JC, Dörner W, Alfermann J, Diecker J, Mootz HD.
Dehling E, et al.
J Mol Biol. 2016 Oct 23;428(21):4345-4360. doi: 10.1016/j.jmb.2016.09.007. Epub 2016 Sep 16.
J Mol Biol. 2016.
PMID: 27647046
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Development of a screening system for inteins active in protein splicing based on intein insertion into the LacZα-peptide.
Neugebauer M, Böcker JK, Matern JC, Pietrokovski S, Mootz HD.
Neugebauer M, et al.
Biol Chem. 2017 Jan 1;398(1):57-67. doi: 10.1515/hsz-2016-0229.
Biol Chem. 2017.
PMID: 27632429
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Withaferin A, a natural compound with anti-tumor activity, is a potent inhibitor of transcription factor C/EBPβ.
Falkenberg KD, Jakobs A, Matern JC, Dörner W, Uttarkar S, Trentmann A, Steinmann S, Coulibaly A, Schomburg C, Mootz HD, Schmidt TJ, Klempnauer KH.
Falkenberg KD, et al.
Biochim Biophys Acta Mol Cell Res. 2017 Jul;1864(7):1349-1358. doi: 10.1016/j.bbamcr.2017.05.003. Epub 2017 May 2.
Biochim Biophys Acta Mol Cell Res. 2017.
PMID: 28476645
Free article.
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