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Schwann cell TRPA1 mediates neuroinflammation that sustains macrophage-dependent neuropathic pain in mice.
De Logu F, Nassini R, Materazzi S, Carvalho Gonçalves M, Nosi D, Rossi Degl'Innocenti D, Marone IM, Ferreira J, Li Puma S, Benemei S, Trevisan G, Souza Monteiro de Araújo D, Patacchini R, Bunnett NW, Geppetti P. De Logu F, et al. Among authors: materazzi s. Nat Commun. 2017 Dec 1;8(1):1887. doi: 10.1038/s41467-017-01739-2. Nat Commun. 2017. PMID: 29192190 Free PMC article.
The TRPA1 channel mediates the analgesic action of dipyrone and pyrazolone derivatives.
Nassini R, Fusi C, Materazzi S, Coppi E, Tuccinardi T, Marone IM, De Logu F, Preti D, Tonello R, Chiarugi A, Patacchini R, Geppetti P, Benemei S. Nassini R, et al. Among authors: materazzi s. Br J Pharmacol. 2015 Jul;172(13):3397-411. doi: 10.1111/bph.13129. Epub 2015 Apr 24. Br J Pharmacol. 2015. PMID: 25765567 Free PMC article.
Keep in Mind TRPA1 When Prescribing Metamizole!
Benemei S, Nassini R, Materazzi S, Geppetti P. Benemei S, et al. Among authors: materazzi s. Pain Pract. 2016 Sep;16(7):E110. doi: 10.1111/papr.12486. Pain Pract. 2016. PMID: 27600926 No abstract available.
128 results