Mateos-Gomez PA - Search Results

1

The helicase domain of Polθ counteracts RPA to promote alt-NHEJ.

Mateos-Gomez PA, Kent T, Deng SK, McDevitt S, Kashkina E, Hoang TM, Pomerantz RT, Sfeir A. Mateos-Gomez PA, et al. Nat Struct Mol Biol. 2017 Dec;24(12):1116-1123. doi: 10.1038/nsmb.3494. Epub 2017 Oct 23. Nat Struct Mol Biol. 2017. PMID: 29058711 Free PMC article.

2

Mammalian polymerase θ promotes alternative NHEJ and suppresses recombination.

Mateos-Gomez PA, Gong F, Nair N, Miller KM, Lazzerini-Denchi E, Sfeir A. Mateos-Gomez PA, et al. Nature. 2015 Feb 12;518(7538):254-7. doi: 10.1038/nature14157. Epub 2015 Feb 2. Nature. 2015. PMID: 25642960 Free PMC article.

3

Polymerase θ is a robust terminal transferase that oscillates between three different mechanisms during end-joining.

Kent T, Mateos-Gomez PA, Sfeir A, Pomerantz RT. Kent T, et al. Elife. 2016 Jun 17;5:e13740. doi: 10.7554/eLife.13740. Elife. 2016. PMID: 27311885 Free PMC article.

4

Nontelomeric role for Rap1 in regulating metabolism and protecting against obesity.

Yeung F, Ramírez CM, Mateos-Gomez PA, Pinzaru A, Ceccarini G, Kabir S, Fernández-Hernando C, Sfeir A. Yeung F, et al. Cell Rep. 2013 Jun 27;3(6):1847-56. doi: 10.1016/j.celrep.2013.05.032. Epub 2013 Jun 20. Cell Rep. 2013. PMID: 23791522 Free PMC article.

5

Inhibition of 53BP1 favors homology-dependent DNA repair and increases CRISPR-Cas9 genome-editing efficiency.

Canny MD, Moatti N, Wan LCK, Fradet-Turcotte A, Krasner D, Mateos-Gomez PA, Zimmermann M, Orthwein A, Juang YC, Zhang W, Noordermeer SM, Seclen E, Wilson MD, Vorobyov A, Munro M, Ernst A, Ng TF, Cho T, Cannon PM, Sidhu SS, Sicheri F, Durocher D. Canny MD, et al. Among authors: mateos gomez pa. Nat Biotechnol. 2018 Jan;36(1):95-102. doi: 10.1038/nbt.4021. Epub 2017 Nov 27. Nat Biotechnol. 2018. PMID: 29176614 Free PMC article.

6

Targeting AMP-activated kinase impacts hepatocellular cancer stem cells induced by long-term treatment with sorafenib.

Bort A, Sánchez BG, Mateos-Gómez PA, Vara-Ciruelos D, Rodríguez-Henche N, Díaz-Laviada I. Bort A, et al. Among authors: mateos gomez pa. Mol Oncol. 2019 May;13(5):1311-1331. doi: 10.1002/1878-0261.12488. Epub 2019 Apr 15. Mol Oncol. 2019. PMID: 30959553 Free PMC article.

7

Long-distance RNA-RNA interactions in the coronavirus genome form high-order structures promoting discontinuous RNA synthesis during transcription.

Mateos-Gomez PA, Morales L, Zuñiga S, Enjuanes L, Sola I. Mateos-Gomez PA, et al. J Virol. 2013 Jan;87(1):177-86. doi: 10.1128/JVI.01782-12. Epub 2012 Oct 10. J Virol. 2013. PMID: 23055566 Free PMC article.

8

Transmissible gastroenteritis coronavirus genome packaging signal is located at the 5' end of the genome and promotes viral RNA incorporation into virions in a replication-independent process.

Morales L, Mateos-Gomez PA, Capiscol C, del Palacio L, Enjuanes L, Sola I. Morales L, et al. J Virol. 2013 Nov;87(21):11579-90. doi: 10.1128/JVI.01836-13. Epub 2013 Aug 21. J Virol. 2013. PMID: 23966403 Free PMC article.

9

The red pepper's spicy ingredient capsaicin activates AMPK in HepG2 cells through CaMKKβ.

Bort A, Sánchez BG, Spínola E, Mateos-Gómez PA, Rodríguez-Henche N, Díaz-Laviada I. Bort A, et al. Among authors: mateos gomez pa. PLoS One. 2019 Jan 29;14(1):e0211420. doi: 10.1371/journal.pone.0211420. eCollection 2019. PLoS One. 2019. PMID: 30695053 Free PMC article.

10

Combination of the natural product capsaicin and docetaxel synergistically kills human prostate cancer cells through the metabolic regulator AMP-activated kinase.

Sánchez BG, Bort A, Mateos-Gómez PA, Rodríguez-Henche N, Díaz-Laviada I. Sánchez BG, et al. Among authors: mateos gomez pa. Cancer Cell Int. 2019 Mar 8;19:54. doi: 10.1186/s12935-019-0769-2. eCollection 2019. Cancer Cell Int. 2019. PMID: 30899201 Free PMC article.

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