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204 results

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Iron accumulation drives fibrosis, senescence and the senescence-associated secretory phenotype.
Maus M, López-Polo V, Mateo L, Lafarga M, Aguilera M, De Lama E, Meyer K, Sola A, Lopez-Martinez C, López-Alonso I, Guasch-Piqueras M, Hernandez-Gonzalez F, Chaib S, Rovira M, Sanchez M, Faner R, Agusti A, Diéguez-Hurtado R, Ortega S, Manonelles A, Engelhardt S, Monteiro F, Stephan-Otto Attolini C, Prats N, Albaiceta G, Cruzado JM, Serrano M. Maus M, et al. Among authors: mateo l. Nat Metab. 2023 Dec;5(12):2111-2130. doi: 10.1038/s42255-023-00928-2. Epub 2023 Dec 14. Nat Metab. 2023. PMID: 38097808 Free PMC article.
Mex3a marks drug-tolerant persister colorectal cancer cells that mediate relapse after chemotherapy.
Álvarez-Varela A, Novellasdemunt L, Barriga FM, Hernando-Momblona X, Cañellas-Socias A, Cano-Crespo S, Sevillano M, Cortina C, Stork D, Morral C, Turon G, Slebe F, Jiménez-Gracia L, Caratù G, Jung P, Stassi G, Heyn H, Tauriello DVF, Mateo L, Tejpar S, Sancho E, Stephan-Otto Attolini C, Batlle E. Álvarez-Varela A, et al. Among authors: mateo l. Nat Cancer. 2022 Sep;3(9):1052-1070. doi: 10.1038/s43018-022-00402-0. Epub 2022 Jun 30. Nat Cancer. 2022. PMID: 35773527 Free article.
The efficacy of chemotherapy is limited by intratumoral senescent cells expressing PD-L2.
Chaib S, López-Domínguez JA, Lalinde-Gutiérrez M, Prats N, Marin I, Boix O, García-Garijo A, Meyer K, Muñoz MI, Aguilera M, Mateo L, Stephan-Otto Attolini C, Llanos S, Pérez-Ramos S, Escorihuela M, Al-Shahrour F, Cash TP, Tchkonia T, Kirkland JL, Abad M, Gros A, Arribas J, Serrano M. Chaib S, et al. Among authors: mateo l. Nat Cancer. 2024 Mar;5(3):448-462. doi: 10.1038/s43018-023-00712-x. Epub 2024 Jan 24. Nat Cancer. 2024. PMID: 38267628 Free PMC article.
Metastatic recurrence in colorectal cancer arises from residual EMP1+ cells.
Cañellas-Socias A, Cortina C, Hernando-Momblona X, Palomo-Ponce S, Mulholland EJ, Turon G, Mateo L, Conti S, Roman O, Sevillano M, Slebe F, Stork D, Caballé-Mestres A, Berenguer-Llergo A, Álvarez-Varela A, Fenderico N, Novellasdemunt L, Jiménez-Gracia L, Sipka T, Bardia L, Lorden P, Colombelli J, Heyn H, Trepat X, Tejpar S, Sancho E, Tauriello DVF, Leedham S, Attolini CS, Batlle E. Cañellas-Socias A, et al. Among authors: mateo l. Nature. 2022 Nov;611(7936):603-613. doi: 10.1038/s41586-022-05402-9. Epub 2022 Nov 9. Nature. 2022. PMID: 36352230 Free article.
Exploring the OncoGenomic Landscape of cancer.
Mateo L, Guitart-Pla O, Duran-Frigola M, Aloy P. Mateo L, et al. Genome Med. 2018 Aug 3;10(1):61. doi: 10.1186/s13073-018-0571-0. Genome Med. 2018. PMID: 30071882 Free PMC article.
A PanorOmic view of personal cancer genomes.
Mateo L, Guitart-Pla O, Pons C, Duran-Frigola M, Mosca R, Aloy P. Mateo L, et al. Nucleic Acids Res. 2017 Jul 3;45(W1):W195-W200. doi: 10.1093/nar/gkx311. Nucleic Acids Res. 2017. PMID: 28453651 Free PMC article.
Bioactivity Profile Similarities to Expand the Repertoire of COVID-19 Drugs.
Duran-Frigola M, Bertoni M, Blanco R, Martínez V, Pauls E, Alcalde V, Turon G, Villegas N, Fernández-Torras A, Pons C, Mateo L, Guitart-Pla O, Badia-I-Mompel P, Gimeno A, Soler N, Brun-Heath I, Zaragoza H, Aloy P. Duran-Frigola M, et al. Among authors: mateo l. J Chem Inf Model. 2020 Dec 28;60(12):5730-5734. doi: 10.1021/acs.jcim.0c00420. Epub 2020 Jul 16. J Chem Inf Model. 2020. PMID: 32672454
Identification and drug-induced reversion of molecular signatures of Alzheimer's disease onset and progression in AppNL-G-F, AppNL-F, and 3xTg-AD mouse models.
Pauls E, Bayod S, Mateo L, Alcalde V, Juan-Blanco T, Sánchez-Soto M, Saido TC, Saito T, Berrenguer-Llergo A, Attolini CS, Gay M, de Oliveira E, Duran-Frigola M, Aloy P. Pauls E, et al. Among authors: mateo l. Genome Med. 2021 Oct 26;13(1):168. doi: 10.1186/s13073-021-00983-y. Genome Med. 2021. PMID: 34702310 Free PMC article.
A community challenge for a pancancer drug mechanism of action inference from perturbational profile data.
Douglass EF Jr, Allaway RJ, Szalai B, Wang W, Tian T, Fernández-Torras A, Realubit R, Karan C, Zheng S, Pessia A, Tanoli Z, Jafari M, Wan F, Li S, Xiong Y, Duran-Frigola M, Bertoni M, Badia-I-Mompel P, Mateo L, Guitart-Pla O, Chung V; DREAM CTD-squared Pancancer Drug Activity Challenge Consortium; Tang J, Zeng J, Aloy P, Saez-Rodriguez J, Guinney J, Gerhard DS, Califano A. Douglass EF Jr, et al. Among authors: mateo l. Cell Rep Med. 2022 Jan 18;3(1):100492. doi: 10.1016/j.xcrm.2021.100492. eCollection 2022 Jan 18. Cell Rep Med. 2022. PMID: 35106508 Free PMC article.
204 results