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21 results

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Page 1
PU.1 controls fibroblast polarization and tissue fibrosis.
Wohlfahrt T, Rauber S, Uebe S, Luber M, Soare A, Ekici A, Weber S, Matei AE, Chen CW, Maier C, Karouzakis E, Kiener HP, Pachera E, Dees C, Beyer C, Daniel C, Gelse K, Kremer AE, Naschberger E, Stürzl M, Butter F, Sticherling M, Finotto S, Kreuter A, Kaplan MH, Jüngel A, Gay S, Nutt SL, Boykin DW, Poon GMK, Distler O, Schett G, Distler JHW, Ramming A. Wohlfahrt T, et al. Among authors: matei ae. Nature. 2019 Feb;566(7744):344-349. doi: 10.1038/s41586-019-0896-x. Epub 2019 Jan 30. Nature. 2019. PMID: 30700907 Free PMC article.
Targeting TGF-β signaling for the treatment of fibrosis.
Györfi AH, Matei AE, Distler JHW. Györfi AH, et al. Among authors: matei ae. Matrix Biol. 2018 Aug;68-69:8-27. doi: 10.1016/j.matbio.2017.12.016. Epub 2018 Jan 31. Matrix Biol. 2018. PMID: 29355590 Review.
The tyrosine phosphatase SHP2 controls TGFβ-induced STAT3 signaling to regulate fibroblast activation and fibrosis.
Zehender A, Huang J, Györfi AH, Matei AE, Trinh-Minh T, Xu X, Li YN, Chen CW, Lin J, Dees C, Beyer C, Gelse K, Zhang ZY, Bergmann C, Ramming A, Birchmeier W, Distler O, Schett G, Distler JHW. Zehender A, et al. Among authors: matei ae. Nat Commun. 2018 Aug 14;9(1):3259. doi: 10.1038/s41467-018-05768-3. Nat Commun. 2018. PMID: 30108215 Free PMC article.
Fibroblast growth factor receptor 3 activates a network of profibrotic signaling pathways to promote fibrosis in systemic sclerosis.
Chakraborty D, Zhu H, Jüngel A, Summa L, Li YN, Matei AE, Zhou X, Huang J, Trinh-Minh T, Chen CW, Lafyatis R, Dees C, Bergmann C, Soare A, Luo H, Ramming A, Schett G, Distler O, Distler JHW. Chakraborty D, et al. Among authors: matei ae. Sci Transl Med. 2020 Sep 30;12(563):eaaz5506. doi: 10.1126/scitranslmed.aaz5506. Sci Transl Med. 2020. PMID: 32998972
Targeting of canonical WNT signaling ameliorates experimental sclerodermatous chronic graft-versus-host disease.
Zhang Y, Shen L, Dreißigacker K, Zhu H, Trinh-Minh T, Meng X, Tran-Manh C, Dees C, Matei AE, Chen CW, Ditschkowski M, Krauss S, Winkler J, Wolff D, Ziemer M, Beilhack A, Karrer S, Herr W, Mackensen A, Schett G, Spriewald BM, Distler JHW. Zhang Y, et al. Among authors: matei ae. Blood. 2021 Apr 29;137(17):2403-2416. doi: 10.1182/blood.2020008720. Blood. 2021. PMID: 33529322 Free article.
X-linked inhibitor of apoptosis protein (XIAP) inhibition in systemic sclerosis (SSc).
Bergmann C, Hallenberger L, Chenguiti Fakhouri S, Merlevede B, Brandt A, Dees C, Zhu H, Zehender A, Zhou X, Schwab A, Chen CW, Györfi AH, Matei AE, Chakraborty D, Trinh-Minh T, Rauber S, Coras R, Bozec A, Kreuter A, Ziemer M, Schett G, Distler JHW. Bergmann C, et al. Among authors: matei ae. Ann Rheum Dis. 2021 Aug;80(8):1048-1056. doi: 10.1136/annrheumdis-2020-219822. Epub 2021 Apr 26. Ann Rheum Dis. 2021. PMID: 33903093
Engrailed 1 coordinates cytoskeletal reorganization to induce myofibroblast differentiation.
Györfi AH, Matei AE, Fuchs M, Liang C, Rigau AR, Hong X, Zhu H, Luber M, Bergmann C, Dees C, Ludolph I, Horch RE, Distler O, Wang J, Bengsch B, Schett G, Kunz M, Distler JHW. Györfi AH, et al. Among authors: matei ae. J Exp Med. 2021 Sep 6;218(9):e20201916. doi: 10.1084/jem.20201916. Epub 2021 Jul 14. J Exp Med. 2021. PMID: 34259830 Free PMC article.
21 results