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Structural basis for elastolytic substrate specificity in rodent alpha-chymases.
Kervinen J, Abad M, Crysler C, Kolpak M, Mahan AD, Masucci JA, Bayoumy S, Cummings MD, Yao X, Olson M, de Garavilla L, Kuo L, Deckman I, Spurlino J. Kervinen J, et al. Among authors: masucci ja. J Biol Chem. 2008 Jan 4;283(1):427-436. doi: 10.1074/jbc.M707157200. Epub 2007 Oct 31. J Biol Chem. 2008. PMID: 17981788 Free article.
Cleaved SLPI, a novel biomarker of chymase activity.
Belkowski SM, Masucci J, Mahan A, Kervinen J, Olson M, de Garavilla L, D'Andrea MR. Belkowski SM, et al. Biol Chem. 2008 Sep;389(9):1219-24. doi: 10.1515/BC.2008.138. Biol Chem. 2008. PMID: 18713008
Dihydroquinone ansamycins: toward resolving the conflict between low in vitro affinity and high cellular potency of geldanamycin derivatives.
Maroney AC, Marugan JJ, Mezzasalma TM, Barnakov AN, Garrabrant TA, Weaner LE, Jones WJ, Barnakova LA, Koblish HK, Todd MJ, Masucci JA, Deckman IC, Galemmo RA Jr, Johnson DL. Maroney AC, et al. Among authors: masucci ja. Biochemistry. 2006 May 2;45(17):5678-85. doi: 10.1021/bi0524969. Biochemistry. 2006. PMID: 16634649
Synthesis and biological evaluation of novel pyridazinone-based alpha4 integrin receptor antagonists.
Gong Y, Barbay JK, Dyatkin AB, Miskowski TA, Kimball ES, Prouty SM, Fisher MC, Santulli RJ, Schneider CR, Wallace NH, Ballentine SA, Hageman WE, Masucci JA, Maryanoff BE, Damiano BP, Andrade-Gordon P, Hlasta DJ, Hornby PJ, He W. Gong Y, et al. Among authors: masucci ja. J Med Chem. 2006 Jun 1;49(11):3402-11. doi: 10.1021/jm060031q. J Med Chem. 2006. PMID: 16722660
N-glucuronidation of the platelet-derived growth factor receptor tyrosine kinase inhibitor 6,7-(dimethoxy-2,4-dihydroindeno[1,2-C]pyrazol-3-yl)-(3-fluoro-phenyl)-amine by human UDP-glucuronosyltransferases.
Yan Z, Caldwell GW, Gauthier D, Leo GC, Mei J, Ho CY, Jones WJ, Masucci JA, Tuman RW, Galemmo RA Jr, Johnson DL. Yan Z, et al. Among authors: masucci ja. Drug Metab Dispos. 2006 May;34(5):748-55. doi: 10.1124/dmd.106.009274. Epub 2006 Feb 2. Drug Metab Dispos. 2006. PMID: 16455802
42 results