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Page 1
TDP-43 Triggers Mitochondrial DNA Release via mPTP to Activate cGAS/STING in ALS.
Yu CH, Davidson S, Harapas CR, Hilton JB, Mlodzianoski MJ, Laohamonthonkul P, Louis C, Low RRJ, Moecking J, De Nardo D, Balka KR, Calleja DJ, Moghaddas F, Ni E, McLean CA, Samson AL, Tyebji S, Tonkin CJ, Bye CR, Turner BJ, Pepin G, Gantier MP, Rogers KL, McArthur K, Crouch PJ, Masters SL. Yu CH, et al. Among authors: masters sl. Cell. 2020 Oct 29;183(3):636-649.e18. doi: 10.1016/j.cell.2020.09.020. Epub 2020 Oct 7. Cell. 2020. PMID: 33031745 Free PMC article.
NLRP1 inflammasome activation induces pyroptosis of hematopoietic progenitor cells.
Masters SL, Gerlic M, Metcalf D, Preston S, Pellegrini M, O'Donnell JA, McArthur K, Baldwin TM, Chevrier S, Nowell CJ, Cengia LH, Henley KJ, Collinge JE, Kastner DL, Feigenbaum L, Hilton DJ, Alexander WS, Kile BT, Croker BA. Masters SL, et al. Immunity. 2012 Dec 14;37(6):1009-23. doi: 10.1016/j.immuni.2012.08.027. Epub 2012 Dec 6. Immunity. 2012. PMID: 23219391 Free PMC article.
Innate immunity.
Masters SL, De Nardo D. Masters SL, et al. Curr Opin Immunol. 2014 Feb;26:v-vi. doi: 10.1016/j.coi.2013.12.006. Epub 2014 Feb 1. Curr Opin Immunol. 2014. PMID: 24495628 No abstract available.
Monogenic autoinflammatory diseases: Cytokinopathies.
Moghaddas F, Masters SL. Moghaddas F, et al. Among authors: masters sl. Cytokine. 2015 Aug;74(2):237-46. doi: 10.1016/j.cyto.2015.02.012. Epub 2015 Mar 23. Cytokine. 2015. PMID: 25814341 Review.
Aberrant actin depolymerization triggers the pyrin inflammasome and autoinflammatory disease that is dependent on IL-18, not IL-1β.
Kim ML, Chae JJ, Park YH, De Nardo D, Stirzaker RA, Ko HJ, Tye H, Cengia L, DiRago L, Metcalf D, Roberts AW, Kastner DL, Lew AM, Lyras D, Kile BT, Croker BA, Masters SL. Kim ML, et al. Among authors: masters sl. J Exp Med. 2015 Jun 1;212(6):927-38. doi: 10.1084/jem.20142384. Epub 2015 May 25. J Exp Med. 2015. PMID: 26008898 Free PMC article.
ATF3 Is a Key Regulator of Macrophage IFN Responses.
Labzin LI, Schmidt SV, Masters SL, Beyer M, Krebs W, Klee K, Stahl R, Lütjohann D, Schultze JL, Latz E, De Nardo D. Labzin LI, et al. Among authors: masters sl. J Immunol. 2015 Nov 1;195(9):4446-55. doi: 10.4049/jimmunol.1500204. Epub 2015 Sep 28. J Immunol. 2015. PMID: 26416280
An aspartyl protease defines a novel pathway for export of Toxoplasma proteins into the host cell.
Coffey MJ, Sleebs BE, Uboldi AD, Garnham A, Franco M, Marino ND, Panas MW, Ferguson DJ, Enciso M, O'Neill MT, Lopaticki S, Stewart RJ, Dewson G, Smyth GK, Smith BJ, Masters SL, Boothroyd JC, Boddey JA, Tonkin CJ. Coffey MJ, et al. Among authors: masters sl. Elife. 2015 Nov 18;4:e10809. doi: 10.7554/eLife.10809. Elife. 2015. PMID: 26576949 Free PMC article.
Regulation of Starch Stores by a Ca(2+)-Dependent Protein Kinase Is Essential for Viable Cyst Development in Toxoplasma gondii.
Uboldi AD, McCoy JM, Blume M, Gerlic M, Ferguson DJ, Dagley LF, Beahan CT, Stapleton DI, Gooley PR, Bacic A, Masters SL, Webb AI, McConville MJ, Tonkin CJ. Uboldi AD, et al. Among authors: masters sl. Cell Host Microbe. 2015 Dec 9;18(6):670-81. doi: 10.1016/j.chom.2015.11.004. Cell Host Microbe. 2015. PMID: 26651943 Free article.
Familial autoinflammation with neutrophilic dermatosis reveals a regulatory mechanism of pyrin activation.
Masters SL, Lagou V, Jéru I, Baker PJ, Van Eyck L, Parry DA, Lawless D, De Nardo D, Garcia-Perez JE, Dagley LF, Holley CL, Dooley J, Moghaddas F, Pasciuto E, Jeandel PY, Sciot R, Lyras D, Webb AI, Nicholson SE, De Somer L, van Nieuwenhove E, Ruuth-Praz J, Copin B, Cochet E, Medlej-Hashim M, Megarbane A, Schroder K, Savic S, Goris A, Amselem S, Wouters C, Liston A. Masters SL, et al. Sci Transl Med. 2016 Mar 30;8(332):332ra45. doi: 10.1126/scitranslmed.aaf1471. Sci Transl Med. 2016. PMID: 27030597 Free article.
Active MLKL triggers the NLRP3 inflammasome in a cell-intrinsic manner.
Conos SA, Chen KW, De Nardo D, Hara H, Whitehead L, Núñez G, Masters SL, Murphy JM, Schroder K, Vaux DL, Lawlor KE, Lindqvist LM, Vince JE. Conos SA, et al. Among authors: masters sl. Proc Natl Acad Sci U S A. 2017 Feb 7;114(6):E961-E969. doi: 10.1073/pnas.1613305114. Epub 2017 Jan 17. Proc Natl Acad Sci U S A. 2017. PMID: 28096356 Free PMC article.
161 results