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Senolytics dasatinib and quercetin in idiopathic pulmonary fibrosis: results of a phase I, single-blind, single-center, randomized, placebo-controlled pilot trial on feasibility and tolerability.
Nambiar A, Kellogg D 3rd, Justice J, Goros M, Gelfond J, Pascual R, Hashmi S, Masternak M, Prata L, LeBrasseur N, Limper A, Kritchevsky S, Musi N, Tchkonia T, Kirkland J. Nambiar A, et al. Among authors: masternak m. EBioMedicine. 2023 Apr;90:104481. doi: 10.1016/j.ebiom.2023.104481. Epub 2023 Feb 28. EBioMedicine. 2023. PMID: 36857968 Free PMC article. Clinical Trial.
Dasatinib and quercetin increase testosterone and sperm concentration in mice.
Garcia DN, Hense JD, Zanini BM, Isola JVV, Pradiee J, Prosczek JB, Alvarado-Rincón JA, Mondadori RG, Mason JB, Brieño-Enríquez MA, Barros CC, Stout MB, Masternak MM, Schneider A. Garcia DN, et al. Among authors: masternak mm. Physiol Int. 2023 May 26;110(2):121-134. doi: 10.1556/2060.2023.00192. Print 2023 Jun 12. Physiol Int. 2023. PMID: 37235453
Senolytics prevent age-associated changes in female mice brain.
Faria OW, de Aguiar MSS, de Mello JE, Alvez FL, Luduvico KP, Garcia DN, Schneider A, Masternak MM, Spanevello RM, Stefanello FM. Faria OW, et al. Among authors: masternak mm. Neurosci Lett. 2024 Mar 15;826:137730. doi: 10.1016/j.neulet.2024.137730. Epub 2024 Mar 12. Neurosci Lett. 2024. PMID: 38485080
Senolytic treatment fails to improve ovarian reserve or fertility in female mice.
Garcia DN, Hense JD, Zanini BM, Isola JVV, Prosczek JB, Ashiqueali S, Oliveira TL, Mason JB, Schadock IC, Barros CC, Stout MB, Masternak MM, Schneider A. Garcia DN, et al. Among authors: masternak mm. Geroscience. 2024 Jun;46(3):3445-3455. doi: 10.1007/s11357-024-01089-0. Epub 2024 Feb 15. Geroscience. 2024. PMID: 38358579 Free PMC article.
Ovarian aging in humans: potential strategies for extending reproductive lifespan.
Cavalcante MB, Sampaio OGM, Câmara FEA, Schneider A, de Ávila BM, Prosczek J, Masternak MM, Campos AR. Cavalcante MB, et al. Among authors: masternak mm. Geroscience. 2023 Aug;45(4):2121-2133. doi: 10.1007/s11357-023-00768-8. Epub 2023 Mar 13. Geroscience. 2023. PMID: 36913129 Free PMC article. Review.
Unique trans-kingdom microbiome structural and functional signatures predict cognitive decline in older adults.
Chaudhari DS, Jain S, Yata VK, Mishra SP, Kumar A, Fraser A, Kociolek J, Dangiolo M, Smith A, Golden A, Masternak MM, Holland P, Agronin M, White-Williams C, Arikawa AY, Labyak CA, Yadav H. Chaudhari DS, et al. Among authors: masternak mm. Geroscience. 2023 Oct;45(5):2819-2834. doi: 10.1007/s11357-023-00799-1. Epub 2023 May 22. Geroscience. 2023. PMID: 37213047 Free PMC article.
Skin assessment in congenital untreated isolated GH deficiency.
Barros-Oliveira CS, de Jesus MJM, Campos VC, Salvatori R, de Souza Araújo AA, Neto RFS, Bartke A, Batista VO, Schneider A, Villar-Gouy KR, Masternak MM, Leal ÂC, Santos LB, Oliveira CRP, Santos EG, Oliveira Simões DA, de Santana Silva B, Aguiar-Oliveira MH. Barros-Oliveira CS, et al. Among authors: masternak mm. Endocrine. 2024 May 4. doi: 10.1007/s12020-024-03840-1. Online ahead of print. Endocrine. 2024. PMID: 38703329
160 results