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Widespread hydroxylation of unstructured lysine-rich protein domains by JMJD6.
Cockman ME, Sugimoto Y, Pegg HB, Masson N, Salah E, Tumber A, Flynn HR, Kirkpatrick JM, Schofield CJ, Ratcliffe PJ. Cockman ME, et al. Among authors: masson n. Proc Natl Acad Sci U S A. 2022 Aug 9;119(32):e2201483119. doi: 10.1073/pnas.2201483119. Epub 2022 Aug 5. Proc Natl Acad Sci U S A. 2022. PMID: 35930668 Free PMC article.
C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation.
Epstein AC, Gleadle JM, McNeill LA, Hewitson KS, O'Rourke J, Mole DR, Mukherji M, Metzen E, Wilson MI, Dhanda A, Tian YM, Masson N, Hamilton DL, Jaakkola P, Barstead R, Hodgkin J, Maxwell PH, Pugh CW, Schofield CJ, Ratcliffe PJ. Epstein AC, et al. Among authors: masson n. Cell. 2001 Oct 5;107(1):43-54. doi: 10.1016/s0092-8674(01)00507-4. Cell. 2001. PMID: 11595184 Free article.
Peptide blockade of HIFalpha degradation modulates cellular metabolism and angiogenesis.
Willam C, Masson N, Tian YM, Mahmood SA, Wilson MI, Bicknell R, Eckardt KU, Maxwell PH, Ratcliffe PJ, Pugh CW. Willam C, et al. Among authors: masson n. Proc Natl Acad Sci U S A. 2002 Aug 6;99(16):10423-8. doi: 10.1073/pnas.162119399. Epub 2002 Jul 29. Proc Natl Acad Sci U S A. 2002. PMID: 12149454 Free PMC article.
Posttranslational hydroxylation of ankyrin repeats in IkappaB proteins by the hypoxia-inducible factor (HIF) asparaginyl hydroxylase, factor inhibiting HIF (FIH).
Cockman ME, Lancaster DE, Stolze IP, Hewitson KS, McDonough MA, Coleman ML, Coles CH, Yu X, Hay RT, Ley SC, Pugh CW, Oldham NJ, Masson N, Schofield CJ, Ratcliffe PJ. Cockman ME, et al. Among authors: masson n. Proc Natl Acad Sci U S A. 2006 Oct 3;103(40):14767-72. doi: 10.1073/pnas.0606877103. Epub 2006 Sep 26. Proc Natl Acad Sci U S A. 2006. PMID: 17003112 Free PMC article.
111 results