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Absence of system xc- on immune cells invading the central nervous system alleviates experimental autoimmune encephalitis.
Merckx E, Albertini G, Paterka M, Jensen C, Albrecht P, Dietrich M, Van Liefferinge J, Bentea E, Verbruggen L, Demuyser T, Deneyer L, Lewerenz J, van Loo G, De Keyser J, Sato H, Maher P, Methner A, Massie A. Merckx E, et al. Among authors: massie a. J Neuroinflammation. 2017 Jan 13;14(1):9. doi: 10.1186/s12974-016-0787-0. J Neuroinflammation. 2017. PMID: 28086920 Free PMC article.
Lifespan extension with preservation of hippocampal function in aged system xc--deficient male mice.
Verbruggen L, Ates G, Lara O, De Munck J, Villers A, De Pauw L, Ottestad-Hansen S, Kobayashi S, Beckers P, Janssen P, Sato H, Zhou Y, Hermans E, Njemini R, Arckens L, Danbolt NC, De Bundel D, Aerts JL, Barbé K, Guillaume B, Ris L, Bentea E, Massie A. Verbruggen L, et al. Among authors: massie a. Mol Psychiatry. 2022 Apr;27(4):2355-2368. doi: 10.1038/s41380-022-01470-5. Epub 2022 Feb 18. Mol Psychiatry. 2022. PMID: 35181756 Free PMC article.
Compartmentalized role of xCT in supporting pancreatic tumor growth, inflammation and mood disturbance in mice.
Lara O, Janssen P, Mambretti M, De Pauw L, Ates G, Mackens L, De Munck J, Walckiers J, Pan Z, Beckers P, Espinet E, Sato H, De Ridder M, Marks DL, Barbé K, Aerts JL, Hermans E, Rooman I, Massie A. Lara O, et al. Among authors: massie a. Brain Behav Immun. 2024 May;118:275-286. doi: 10.1016/j.bbi.2024.03.001. Epub 2024 Mar 4. Brain Behav Immun. 2024. PMID: 38447884 Free article.
Comparative analysis of antibodies to xCT (Slc7a11): Forewarned is forearmed.
Van Liefferinge J, Bentea E, Demuyser T, Albertini G, Follin-Arbelet V, Holmseth S, Merckx E, Sato H, Aerts JL, Smolders I, Arckens L, Danbolt NC, Massie A. Van Liefferinge J, et al. Among authors: massie a. J Comp Neurol. 2016 Apr 1;524(5):1015-32. doi: 10.1002/cne.23889. Epub 2015 Oct 23. J Comp Neurol. 2016. PMID: 26494316
Slc7a11 (xCT) protein expression is not altered in the depressed brain and system xc- deficiency does not affect depression-associated behaviour in the corticosterone mouse model.
Demuyser T, Deneyer L, Bentea E, Albertini G, Femenia T, Walrave L, Sato H, Danbolt NC, De Bundel D, Michotte A, Lindskog M, Massie A, Smolders I. Demuyser T, et al. Among authors: massie a. World J Biol Psychiatry. 2019 Jun;20(5):381-392. doi: 10.1080/15622975.2017.1371332. Epub 2017 Sep 27. World J Biol Psychiatry. 2019. PMID: 28882088
432 results