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PI(3,4)P2-mediated cytokinetic abscission prevents early senescence and cataract formation.
Gulluni F, Prever L, Li H, Krafcikova P, Corrado I, Lo WT, Margaria JP, Chen A, De Santis MC, Cnudde SJ, Fogerty J, Yuan A, Massarotti A, Sarijalo NT, Vadas O, Williams RL, Thelen M, Powell DR, Schueler M, Wiesener MS, Balla T, Baris HN, Tiosano D, McDermott BM Jr, Perkins BD, Ghigo A, Martini M, Haucke V, Boura E, Merlo GR, Buchner DA, Hirsch E. Gulluni F, et al. Among authors: massarotti a. Science. 2021 Dec 10;374(6573):eabk0410. doi: 10.1126/science.abk0410. Epub 2021 Dec 10. Science. 2021. PMID: 34882480 Free PMC article.
Identification of a Potent Phosphoinositide 3-Kinase Pan Inhibitor Displaying a Strategic Carboxylic Acid Group and Development of Its Prodrugs.
Pirali T, Ciraolo E, Aprile S, Massarotti A, Berndt A, Griglio A, Serafini M, Mercalli V, Landoni C, Campa CC, Margaria JP, Silva RL, Grosa G, Sorba G, Williams R, Hirsch E, Tron GC. Pirali T, et al. Among authors: massarotti a. ChemMedChem. 2017 Sep 21;12(18):1542-1554. doi: 10.1002/cmdc.201700340. Epub 2017 Aug 31. ChemMedChem. 2017. PMID: 28857471 Free PMC article.
Essential Medicinal Chemistry of Essential Medicines.
Serafini M, Cargnin S, Massarotti A, Pirali T, Genazzani AA. Serafini M, et al. Among authors: massarotti a. J Med Chem. 2020 Sep 24;63(18):10170-10187. doi: 10.1021/acs.jmedchem.0c00415. Epub 2020 May 12. J Med Chem. 2020. PMID: 32352778 Free PMC article. Review.
ZINClick v.18: Expanding Chemical Space of 1,2,3-Triazoles.
Levré D, Arcisto C, Mercalli V, Massarotti A. Levré D, et al. Among authors: massarotti a. J Chem Inf Model. 2019 May 28;59(5):1697-1702. doi: 10.1021/acs.jcim.8b00615. Epub 2018 Nov 27. J Chem Inf Model. 2019. PMID: 30419167 Free article.
Estrogenic analogues synthesized by click chemistry.
Pirali T, Gatti S, Di Brisco R, Tacchi S, Zaninetti R, Brunelli E, Massarotti A, Sorba G, Canonico PL, Moro L, Genazzani AA, Tron GC, Billington RA. Pirali T, et al. Among authors: massarotti a. ChemMedChem. 2007 Apr;2(4):437-40. doi: 10.1002/cmdc.200600192. ChemMedChem. 2007. PMID: 17278167 No abstract available.
63 results