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A lipoglycopeptide antibiotic for Gram-positive biofilm-related infections.
Blaskovich MAT, Hansford KA, Butler MS, Ramu S, Kavanagh AM, Jarrad AM, Prasetyoputri A, Pitt ME, Huang JX, Lindahl F, Ziora ZM, Bradford T, Muldoon C, Rajaratnam P, Pelingon R, Edwards DJ, Zhang B, Amado M, Elliott AG, Zuegg J, Coin L, Woischnig AK, Khanna N, Breidenstein E, Stincone A, Mason C, Khan N, Cho HK, Karau MJ, Greenwood-Quaintance KE, Patel R, Wootton M, James ML, Hutton ML, Lyras D, Ogunniyi AD, Mahdi LK, Trott DJ, Wu X, Niles S, Lewis K, Smith JR, Barber KE, Yim J, Rice SA, Rybak MJ, Ishmael CR, Hori KR, Bernthal NM, Francis KP, Roberts JA, Paterson DL, Cooper MA. Blaskovich MAT, et al. Among authors: mason c. Sci Transl Med. 2022 Sep 14;14(662):eabj2381. doi: 10.1126/scitranslmed.abj2381. Epub 2022 Sep 14. Sci Transl Med. 2022. PMID: 36103517
High-density transposon libraries utilising outward-oriented promoters identify mechanisms of action and resistance to antimicrobials.
Coward C, Dharmalingham G, Abdulle O, Avis T, Beisken S, Breidenstein E, Carli N, Figueiredo L, Jones D, Khan N, Malara S, Martins J, Nagalingam N, Turner K, Wain J, Williams D, Powell D, Mason C. Coward C, et al. Among authors: mason c. FEMS Microbiol Lett. 2020 Dec 14;367(22):fnaa185. doi: 10.1093/femsle/fnaa185. FEMS Microbiol Lett. 2020. PMID: 33186989 Free PMC article.
Targeted microbiome-sparing antibiotics.
Avis T, Wilson FX, Khan N, Mason CS, Powell DJ. Avis T, et al. Drug Discov Today. 2021 Sep;26(9):2198-2203. doi: 10.1016/j.drudis.2021.07.016. Epub 2021 Jul 28. Drug Discov Today. 2021. PMID: 34329771 Free article. Review.
Machine learning-powered antibiotics phenotypic drug discovery.
Zoffmann S, Vercruysse M, Benmansour F, Maunz A, Wolf L, Blum Marti R, Heckel T, Ding H, Truong HH, Prummer M, Schmucki R, Mason CS, Bradley K, Jacob AI, Lerner C, Araujo Del Rosario A, Burcin M, Amrein KE, Prunotto M. Zoffmann S, et al. Among authors: mason cs. Sci Rep. 2019 Mar 21;9(1):5013. doi: 10.1038/s41598-019-39387-9. Sci Rep. 2019. PMID: 30899034 Free PMC article.
Macrophage PET imaging in mouse models of cardiovascular disease and cancer with an apolipoprotein-inspired radiotracer.
Toner YC, Prévot G, van Leent MMT, Munitz J, Oosterwijk R, Verschuur AVD, van Elsas Y, Peric V, Maas RJF, Ranzenigo A, Morla-Folch J, Wang W, Umali M, de Dreu A, Fernandes JC, Sullivan NAT, Maier A, Mason C, Reiner T, Fayad ZA, Mulder WJM, Teunissen AJP, Pérez-Medina C. Toner YC, et al. Among authors: mason c. Npj Imaging. 2024;2(1):12. doi: 10.1038/s44303-024-00009-3. Epub 2024 May 15. Npj Imaging. 2024. PMID: 38765879 Free PMC article.
Inspiration4 data access through the NASA Open Science Data Repository.
Sanders LM, Grigorev KA, Scott RT, Saravia-Butler AM, Polo SL, Gilbert R, Overbey EG, Kim J, Mason CE, Costes SV. Sanders LM, et al. Among authors: mason ce. NPJ Microgravity. 2024 May 14;10(1):56. doi: 10.1038/s41526-024-00393-5. NPJ Microgravity. 2024. PMID: 38744887 Free PMC article.
1,954 results