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G6PD variant distribution in sub-Saharan Africa and potential risks of using chloroquine/hydroxychloroquine based treatments for COVID-19.
da Rocha J, Othman H, Tiemessen CT, Botha G, Ramsay M, Masimirembwa C, Adebamowo C, Choudhury A, Brandenburg JT, Matshaba M, Simo G, Gamo FJ, Hazelhurst S; H3Africa Consortium. da Rocha J, et al. Among authors: masimirembwa c. medRxiv [Preprint]. 2020 Jun 2:2020.05.27.20114066. doi: 10.1101/2020.05.27.20114066. medRxiv. 2020. PMID: 32577690 Free PMC article. Updated. Preprint.
G6PD distribution in sub-Saharan Africa and potential risks of using chloroquine/hydroxychloroquine based treatments for COVID-19.
da Rocha JEB, Othman H, Tiemessen CT, Botha G, Ramsay M, Masimirembwa C, Adebamowo C, Choudhury A, Brandenburg JT, Matshaba M, Simo G, Gamo FJ, Hazelhurst S; as members of the H3Africa Consortium. da Rocha JEB, et al. Among authors: masimirembwa c. Pharmacogenomics J. 2021 Dec;21(6):649-656. doi: 10.1038/s41397-021-00242-8. Epub 2021 Jul 23. Pharmacogenomics J. 2021. PMID: 34302047 Free PMC article.
Investigation of the Differences in the Pharmacokinetics of CYP2D6 Substrates, Desipramine, and Dextromethorphan in Healthy African Subjects Carrying the Allelic Variants CYP2D6*17 and CYP2D6*29, When Compared with Normal Metabolizers.
Marasanapalle VP, Masimirembwa C, Sivasubramanian R, Sayyed S, Weinzierl-Hinum A, Mehta D, Kapungu NN, Kanji C, Thelingwani R, Zack J. Marasanapalle VP, et al. Among authors: masimirembwa c. J Clin Pharmacol. 2024 May;64(5):578-589. doi: 10.1002/jcph.2366. Epub 2023 Oct 25. J Clin Pharmacol. 2024. PMID: 37803948
The African Liver Tissue Biorepository Consortium: Capacitating Population-Appropriate Drug Metabolism, Pharmacokinetics, and Pharmacogenetics Research in Drug Discovery and Development.
Masimirembwa C, Ramsay M, Botha J, Ellis E, Etheredge H, Hurrell T, Kanji CR, Kapungu NN, Maher H, Mthembu B, Naidoo J, Scholefield J, Rambarran S, van der Schyff F, Smyth N, Strobele B, Thelingwani RS, Loveland J, Fabian J. Masimirembwa C, et al. Drug Metab Dispos. 2023 Dec;51(12):1551-1560. doi: 10.1124/dmd.123.001400. Epub 2023 Sep 26. Drug Metab Dispos. 2023. PMID: 37751997
124 results