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Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies LRRC4C, LHX5-AS1 and nominates ancestry-specific loci PTPRK , GRB14 , and KIAA0825 as novel risk loci for Alzheimer's disease: the Alzheimer's Disease Genetics Consortium.
Rajabli F, Benchek P, Tosto G, Kushch N, Sha J, Bazemore K, Zhu C, Lee WP, Haut J, Hamilton-Nelson KL, Wheeler NR, Zhao Y, Farrell JJ, Grunin MA, Leung YY, Kuksa PP, Li D, Lucio da Fonseca E, Mez JB, Palmer EL, Pillai J, Sherva RM, Song YE, Zhang X, Iqbal T, Pathak O, Valladares O, Kuzma AB, Abner E, Adams PM, Aguirre A, Albert MS, Albin RL, Allen M, Alvarez L, Apostolova LG, Arnold SE, Asthana S, Atwood CS, Ayres G, Baldwin CT, Barber RC, Barnes LL, Barral S, Beach TG, Becker JT, Beecham GW, Beekly D, Benitez BA, Bennett D, Bertelson J, Bird TD, Blacker D, Boeve BF, Bowen JD, Boxer A, Brewer J, Burke JR, Burns JM, Buxbaum JD, Cairns NJ, Cantwell LB, Cao C, Carlson CS, Carlsson CM, Carney RM, Carrasquillo MM, Chasse S, Chesselet MF, Chin NA, Chui HC, Chung J, Craft S, Crane PK, Cribbs DH, Crocco EA, Cruchaga C, Cuccaro ML, Cullum M, Darby E, Davis B, De Jager PL, DeCarli C, DeToledo J, Dick M, Dickson DW, Dombroski BA, Doody RS, Duara R, Ertekin-Taner N, Evans DA, Faber KM, Fairchild TJ, Fallon KB, Fardo DW, Farlow MR, Fernandez-Hernandez V, Ferris S, Foroud TM, Frosch MP, Fulton-Howard B, Galasko DR, Gamboa A, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Goate AM, Grabowski TJ,… See abstract for full author list ➔ Rajabli F, et al. Among authors: mash dc. medRxiv [Preprint]. 2023 Jul 8:2023.07.06.23292311. doi: 10.1101/2023.07.06.23292311. medRxiv. 2023. PMID: 37461624 Free PMC article. Preprint.
Cell type specific transcriptomic differences in depression show similar patterns between males and females but implicate distinct cell types and genes.
Maitra M, Mitsuhashi H, Rahimian R, Chawla A, Yang J, Fiori LM, Davoli MA, Perlman K, Aouabed Z, Mash DC, Suderman M, Mechawar N, Turecki G, Nagy C. Maitra M, et al. Among authors: mash dc. Nat Commun. 2023 May 22;14(1):2912. doi: 10.1038/s41467-023-38530-5. Nat Commun. 2023. PMID: 37217515 Free PMC article.
Single Nucleus Transcriptomics Reveals Pervasive Glial Activation in Opioid Overdose Cases.
Wei J, Lambert TY, Valada A, Patel N, Walker K, Lenders J, Schmidt CJ, Iskhakova M, Alazizi A, Mair-Meijers H, Mash DC, Luca F, Pique-Regi R, Bannon MJ, Akbarian S. Wei J, et al. Among authors: mash dc. bioRxiv [Preprint]. 2023 Mar 9:2023.03.07.531400. doi: 10.1101/2023.03.07.531400. bioRxiv. 2023. PMID: 36945611 Free PMC article. Preprint.
Low Dopamine D2 Receptor Expression Drives Gene Networks Related to GABA, cAMP, Growth and Neuroinflammation in Striatal Indirect Pathway Neurons.
Guerri L, Dobbs LK, da Silva E Silva DA, Meyers A, Ge A, Lecaj L, Djakuduel C, Islek D, Hipolito D, Martinez AB, Shen PH, Marietta CA, Garamszegi SP, Capobianco E, Jiang Z, Schwandt M, Mash DC, Alvarez VA, Goldman D. Guerri L, et al. Among authors: mash dc. Biol Psychiatry Glob Open Sci. 2022 Sep 8;3(4):1104-1115. doi: 10.1016/j.bpsgos.2022.08.010. eCollection 2023 Oct. Biol Psychiatry Glob Open Sci. 2022. PMID: 37881572 Free PMC article.
Structure-Activity Relationships of Dopamine Transporter Pharmacological Chaperones.
Sutton C, Williams EQ, Homsi H, Beerepoot P, Nazari R, Han D, Ramsey AJ, Mash DC, Olson DE, Blough B, Salahpour A. Sutton C, et al. Among authors: mash dc. Front Cell Neurosci. 2022 May 9;16:832536. doi: 10.3389/fncel.2022.832536. eCollection 2022. Front Cell Neurosci. 2022. PMID: 35614973 Free PMC article.
Single nucleus multi-omics identifies human cortical cell regulatory genome diversity.
Luo C, Liu H, Xie F, Armand EJ, Siletti K, Bakken TE, Fang R, Doyle WI, Stuart T, Hodge RD, Hu L, Wang BA, Zhang Z, Preissl S, Lee DS, Zhou J, Niu SY, Castanon R, Bartlett A, Rivkin A, Wang X, Lucero J, Nery JR, Davis DA, Mash DC, Satija R, Dixon JR, Linnarsson S, Lein E, Behrens MM, Ren B, Mukamel EA, Ecker JR. Luo C, et al. Among authors: mash dc. Cell Genom. 2022 Mar 9;2(3):100107. doi: 10.1016/j.xgen.2022.100107. Cell Genom. 2022. PMID: 35419551 Free PMC article.
286 results