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New approach methodologies (NAMs) for human-relevant biokinetics predictions. Meeting the paradigm shift in toxicology towards an animal-free chemical risk assessment.
Punt A, Bouwmeester H, Blaauboer BJ, Coecke S, Hakkert B, Hendriks DFG, Jennings P, Kramer NI, Neuhoff S, Masereeuw R, Paini A, Peijnenburg AACM, Rooseboom M, Shuler ML, Sorrell I, Spee B, Strikwold M, Van der Meer AD, Van der Zande M, Vinken M, Yang H, Bos PMJ, Heringa MB. Punt A, et al. Among authors: masereeuw r. ALTEX. 2020;37(4):607-622. doi: 10.14573/altex.2003242. Epub 2020 Jun 8. ALTEX. 2020. PMID: 32521035 Free article.
Bioengineered bile ducts recapitulate key cholangiocyte functions.
Chen C, Jochems PGM, Salz L, Schneeberger K, Penning LC, van de Graaf SFJ, Beuers U, Clevers H, Geijsen N, Masereeuw R, Spee B. Chen C, et al. Among authors: masereeuw r. Biofabrication. 2018 Jun 12;10(3):034103. doi: 10.1088/1758-5090/aac8fd. Biofabrication. 2018. PMID: 29848792
Tissue-Engineered Bile Ducts for Disease Modeling and Therapy.
Wang Z, Faria J, Penning LC, Masereeuw R, Spee B. Wang Z, et al. Among authors: masereeuw r. Tissue Eng Part C Methods. 2021 Feb;27(2):59-76. doi: 10.1089/ten.TEC.2020.0283. Epub 2021 Feb 2. Tissue Eng Part C Methods. 2021. PMID: 33267737 Review.
Safer chemicals using less animals: kick-off of the European ONTOX project.
Vinken M, Benfenati E, Busquet F, Castell J, Clevert DA, de Kok TM, Dirven H, Fritsche E, Geris L, Gozalbes R, Hartung T, Jennen D, Jover R, Kandarova H, Kramer N, Krul C, Luechtefeld T, Masereeuw R, Roggen E, Schaller S, Vanhaecke T, Yang C, Piersma AH. Vinken M, et al. Among authors: masereeuw r. Toxicology. 2021 Jun 30;458:152846. doi: 10.1016/j.tox.2021.152846. Epub 2021 Jun 30. Toxicology. 2021. PMID: 34216698 Free article. Review.
COVID-19 through Adverse Outcome Pathways: Building networks to better understand the disease - 3rd CIAO AOP Design Workshop.
Clerbaux LA, Amigó N, Amorim MJ, Bal-Price A, Batista Leite S, Beronius A, Bezemer GFG, Bostroem AC, Carusi A, Coecke S, Concha R, Daskalopoulos EP, De Bernardi F, Edrosa E, Edwards SW, Filipovska J, Garcia-Reyero N, Gavins FNE, Halappanavar S, Hargreaves AJ, Hogberg HT, Huynh MT, Jacobson D, Josephs-Spaulding J, Kim YJ, Kong HJ, Krebs CE, Lam A, Landesmann B, Layton A, Lee YO, Macmillan DS, Mantovani A, Margiotta-Casaluci L, Martens M, Masereeuw R, Mayasich SA, Mei LM, Mortensen H, Munoz Pineiro A, Nymark P, Ohayon E, Ojasi J, Paini A, Parissis N, Parvatam S, Pistollato F, Sachana M, Sørli JB, Sullivan KM, Sund J, Tanabe S, Tsaioun K, Vinken M, Viviani L, Waspe J, Willett C, Wittwehr C. Clerbaux LA, et al. Among authors: masereeuw r. ALTEX. 2022;39(2):322–335. doi: 10.14573/altex.2112161. Epub 2022 Jan 3. ALTEX. 2022. PMID: 35032963 Free PMC article.
Development of an adverse outcome pathway network for nephrotoxicity.
Barnes DA, Firman JW, Belfield SJ, Cronin MTD, Vinken M, Janssen MJ, Masereeuw R. Barnes DA, et al. Among authors: masereeuw r. Arch Toxicol. 2024 Mar;98(3):929-942. doi: 10.1007/s00204-023-03637-7. Epub 2024 Jan 10. Arch Toxicol. 2024. PMID: 38197913 Free PMC article.
Cholangiocyte organoids to study drug-induced injury.
Wang Z, Xing C, van der Laan LJW, Verstegen MMA, Spee B, Masereeuw R. Wang Z, et al. Among authors: masereeuw r. Stem Cell Res Ther. 2024 Mar 13;15(1):78. doi: 10.1186/s13287-024-03692-6. Stem Cell Res Ther. 2024. PMID: 38475870 Free PMC article.
The application of organ-on-chip models for the prediction of human pharmacokinetic profiles during drug development.
Keuper-Navis M, Walles M, Poller B, Myszczyszyn A, van der Made TK, Donkers J, Eslami Amirabadi H, Wilmer MJ, Aan S, Spee B, Masereeuw R, van de Steeg E. Keuper-Navis M, et al. Among authors: masereeuw r. Pharmacol Res. 2023 Sep;195:106853. doi: 10.1016/j.phrs.2023.106853. Epub 2023 Jul 18. Pharmacol Res. 2023. PMID: 37473876 Free article. Review.
262 results