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Development and validation of bioengineered intestinal tubules for translational research aimed at safety and efficacy testing of drugs and nutrients.
Jochems PGM, van Bergenhenegouwen J, van Genderen AM, Eis ST, Wilod Versprille LJF, Wichers HJ, Jeurink PV, Garssen J, Masereeuw R. Jochems PGM, et al. Among authors: masereeuw r. Toxicol In Vitro. 2019 Oct;60:1-11. doi: 10.1016/j.tiv.2019.04.019. Epub 2019 May 6. Toxicol In Vitro. 2019. PMID: 31071426 Free article.
Proximal tubular efflux transporters involved in renal excretion of p-cresyl sulfate and p-cresyl glucuronide: Implications for chronic kidney disease pathophysiology.
Mutsaers HA, Caetano-Pinto P, Seegers AE, Dankers AC, van den Broek PH, Wetzels JF, van den Brand JA, van den Heuvel LP, Hoenderop JG, Wilmer MJ, Masereeuw R. Mutsaers HA, et al. Among authors: masereeuw r. Toxicol In Vitro. 2015 Oct;29(7):1868-77. doi: 10.1016/j.tiv.2015.07.020. Epub 2015 Jul 26. Toxicol In Vitro. 2015. PMID: 26216510
Bioengineered bile ducts recapitulate key cholangiocyte functions.
Chen C, Jochems PGM, Salz L, Schneeberger K, Penning LC, van de Graaf SFJ, Beuers U, Clevers H, Geijsen N, Masereeuw R, Spee B. Chen C, et al. Among authors: masereeuw r. Biofabrication. 2018 Jun 12;10(3):034103. doi: 10.1088/1758-5090/aac8fd. Biofabrication. 2018. PMID: 29848792
Remote sensing and signaling in kidney proximal tubules stimulates gut microbiome-derived organic anion secretion.
Jansen J, Jansen K, Neven E, Poesen R, Othman A, van Mil A, Sluijter J, Sastre Torano J, Zaal EA, Berkers CR, Esser D, Wichers HJ, van Ede K, van Duursen M, Burtey S, Verhaar MC, Meijers B, Masereeuw R. Jansen J, et al. Among authors: masereeuw r. Proc Natl Acad Sci U S A. 2019 Aug 6;116(32):16105-16110. doi: 10.1073/pnas.1821809116. Epub 2019 Jul 24. Proc Natl Acad Sci U S A. 2019. PMID: 31341083 Free PMC article.
Kidney-based in vitro models for drug-induced toxicity testing.
Faria J, Ahmed S, Gerritsen KGF, Mihaila SM, Masereeuw R. Faria J, et al. Among authors: masereeuw r. Arch Toxicol. 2019 Dec;93(12):3397-3418. doi: 10.1007/s00204-019-02598-0. Epub 2019 Oct 29. Arch Toxicol. 2019. PMID: 31664498 Review.
A combined microphysiological-computational omics approach in dietary protein evaluation.
Jochems PGM, Keusters WR, America AHP, Rietveld PCS, Bastiaan-Net S, Ariëns RMC, Tomassen MMM, Lewis F, Li Y, Westphal KGC, Garssen J, Wichers HJ, van Bergenhenegouwen J, Masereeuw R. Jochems PGM, et al. Among authors: masereeuw r. NPJ Sci Food. 2020 Dec 17;4(1):22. doi: 10.1038/s41538-020-00082-z. NPJ Sci Food. 2020. PMID: 33335099 Free PMC article.
262 results