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The PET tracer [11C]MK-6884 quantifies M4 muscarinic receptor in rhesus monkeys and patients with Alzheimer's disease.
Li W, Wang Y, Lohith TG, Zeng Z, Tong L, Mazzola R, Riffel K, Miller P, Purcell M, Holahan M, Haley H, Gantert L, Hesk D, Ren S, Morrow J, Uslaner J, Struyk A, Wai JM, Rudd MT, Tellers DM, McAvoy T, Bormans G, Koole M, Van Laere K, Serdons K, de Hoon J, Declercq R, De Lepeleire I, Pascual MB, Zanotti-Fregonara P, Yu M, Arbones V, Masdeu JC, Cheng A, Hussain A, Bueters T, Anderson MS, Hostetler ED, Basile AS. Li W, et al. Among authors: masdeu jc. Sci Transl Med. 2022 Jan 12;14(627):eabg3684. doi: 10.1126/scitranslmed.abg3684. Epub 2022 Jan 12. Sci Transl Med. 2022. PMID: 35020407
The validity of 18F-GE180 as a TSPO imaging agent.
Zanotti-Fregonara P, Veronese M, Pascual B, Rostomily RC, Turkheimer F, Masdeu JC. Zanotti-Fregonara P, et al. Among authors: masdeu jc. Eur J Nucl Med Mol Imaging. 2019 Jun;46(6):1205-1207. doi: 10.1007/s00259-019-4268-4. Epub 2019 Jan 17. Eur J Nucl Med Mol Imaging. 2019. PMID: 30656358 No abstract available.
Multimodal 18F-AV-1451 and MRI Findings in Nonfluent Variant of Primary Progressive Aphasia: Possible Insights on Nodal Propagation of Tau Protein Across the Syntactic Network.
Pascual B, Funk Q, Zanotti-Fregonara P, Pal N, Rockers E, Yu M, Spann B, Román GC, Schulz PE, Karmonik C, Appel SH, Masdeu JC. Pascual B, et al. Among authors: masdeu jc. J Nucl Med. 2020 Feb;61(2):263-269. doi: 10.2967/jnumed.118.225508. Epub 2019 Jul 26. J Nucl Med. 2020. PMID: 31350322 Free PMC article.
Anatomy of 18F-GE180, a failed radioligand for the TSPO protein.
Zanotti-Fregonara P, Pascual B, Rostomily RC, Rizzo G, Veronese M, Masdeu JC, Turkheimer F. Zanotti-Fregonara P, et al. Among authors: masdeu jc. Eur J Nucl Med Mol Imaging. 2020 Sep;47(10):2233-2236. doi: 10.1007/s00259-020-04732-y. Epub 2020 Feb 22. Eur J Nucl Med Mol Imaging. 2020. PMID: 32088848 No abstract available.
Neuroinflammation is highest in areas of disease progression in semantic dementia.
Pascual B, Funk Q, Zanotti-Fregonara P, Cykowski MD, Veronese M, Rockers E, Bradbury K, Yu M, Nakawah MO, Román GC, Schulz PE, Arumanayagam AS, Beers D, Faridar A, Fujita M, Appel SH, Masdeu JC. Pascual B, et al. Among authors: masdeu jc. Brain. 2021 Jun 22;144(5):1565-1575. doi: 10.1093/brain/awab057. Brain. 2021. PMID: 33824991
206 results