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Phosphotyrosine phosphatase inhibitor bisperoxovanadium endows myogenic cells with enhanced muscle stem cell functions via epigenetic modulation of Sca-1 and Pw1 promoters.
Smeriglio P, Alonso-Martin S, Masciarelli S, Madaro L, Iosue I, Marrocco V, Relaix F, Fazi F, Marazzi G, Sassoon DA, Bouché M. Smeriglio P, et al. Among authors: masciarelli s. FASEB J. 2016 Apr;30(4):1404-15. doi: 10.1096/fj.15-275420. Epub 2015 Dec 15. FASEB J. 2016. PMID: 26672000
Moreover, we found that BpV treatment induces specific activating chromatin modifications at the promoter regions of genes associated with stem cell fate, includingSca-1andPw1 Thus, our findings indicate that BpV resets the cell fate program by specific epigenetic regulations, su …
Moreover, we found that BpV treatment induces specific activating chromatin modifications at the promoter regions of genes associated with s …
Thymic Epithelial Tumors phenotype relies on miR-145-5p epigenetic regulation.
Bellissimo T, Ganci F, Gallo E, Sacconi A, Tito C, De Angelis L, Pulito C, Masciarelli S, Diso D, Anile M, Petrozza V, Giangaspero F, Pescarmona E, Facciolo F, Venuta F, Marino M, Blandino G, Fazi F. Bellissimo T, et al. Among authors: masciarelli s. Mol Cancer. 2017 May 10;16(1):88. doi: 10.1186/s12943-017-0655-2. Mol Cancer. 2017. PMID: 28486946 Free PMC article.
44 results